CS1P1 PET Studies of Neuroinflammation in Parkinson Disease

Status Enrolling by invitation

Clinical Trial Summary

Parkinson disease (PD) is a progressive neurological disorder strongly linked to advancing age that results in decline in mobility and thinking. Based on prior research, the investigators think that small amounts of inflammation in the brain may contribute to the mobility and thinking problems in people with PD. They are trying to measure inflammation in the brain in order to understand how this inflammation could be contributing to the symptoms of PD. This study involves a brain positron emission tomography (PET) scan with a new, investigational radioactive tracer called [11C]-CS1P1 to identify inflammation in the brain.The goal of this project is to quantify neuroinflammation with [11C]-CS1P1 PET and compare to motor and cognitive function in participants with various stages of severity of PD compared to controls.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Parkinson Disease

Clinical Trial Details

NCT number	NCT06084533
Study type	Observational
Source	Washington University School of Medicine
Contact
Status	Enrolling by invitation
Phase
Start date	January 10, 2024
Completion date	February 28, 2029

View Details

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