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Effect of Aerobic Training on Oxidative Stress Markers in Patients With Parkinson's Disease

Parkinson Disease Clinical Trial

Official title:
The Effect of Aerobic Training on Total Antioxidant Status, Total Oxidant Status, Glutathione, Oxidative Glutathione and Zonulin Levels in Patients With Parkinson's Disease

Clinical Trial Summary

Parkinson's disease is a chronic, neurodegenerative disorder characterized with the loss of dopamine-producing neurons. This loss is likely to be related with several environmental and genetic factors. One of the most important factor that is responsible for the initation and progression of the disease is oxidative stress. Exercise training, especially aerobic training, can change the levels of oxidative markers because exercise can lead to decrease oxidative stress in patients with Parkinson's disease. Therefore, this study aims to investigate (1) the effect of aerobic training on total antioxidant status, total oxidant status, glutathione, oxidative glutathione, and zonulin levels, (2) the relationship between the change of motor symptoms and disease severity and the change of total antioxidant status, total oxidant status, glutathione, oxidative glutathione, and zonulin levels.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05511402
Study type Interventional
Source Saglik Bilimleri Universitesi
Contact Fatih Soke, Asst. Prof.
Phone +90 506 932 81 02
Email fatih.soke@sbu.edu.tr
Status Not yet recruiting
Phase N/A
Start date August 25, 2022
Completion date December 10, 2022
View Details
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