Correlation Between Non-motor Symptoms and Malnutrition in Patients With Parkinson's Disease

Parkinson Disease Clinical Trial

Official title:

Correlation Between Non-motor Symptoms and Malnutrition in Patients With Parkinson's Disease

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04934592
• Other study ID #: 2020-376
• Status: Recruiting
• Start date: June 30, 2020
• Est. completion date: November 30, 2021

Study information

• Verified date: May 2021
• Source: Second Affiliated Hospital, School of Medicine, Zhejiang University
• Contact: Qiaomin Tang
• Phone: 13957108417
• Email: julia4711[@]126.com
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

This study used Mini Nutrition Assessment (MNA) , Nutrition risk screening 2002(NRS-2002) and Non-motor Symptom Quest (NMSquest) to investigate the nutritional status of patients with Parkinson's disease, to analyze the correlation between non-motor symptoms and malnutrition in patients with Parkinson's disease (PD) , and to provide evidence for clinical treatment and early nutritional intervention.

Description:

Data were collected by questionnaire survey.For arkinson patients who were admitted to the facility between June 2020 and July 2021 were targeted. This study used convenience sampling and included criteria: length of stay > 24 hours; Parkinson patients who met Chinese diagnostic criteria for Parkinson's disease (2016 edition) ; willing participants and able to complete the scale. Exclusion criteria: parkinsonism caused by cerebrovascular disease, encephalitis, traumatic brain injury, complete transfusion of blood, plasma, albumin within one month, severe gastrointestinal disease, metabolic disease, and other wasting diseases; Patients with critical illness, severe cognitive impairment, and inability to communicate. The study was approved by the medical ethics committee with the informed consent of all selected individuals and their families

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 85
• Est. completion date: November 30, 2021
• Est. primary completion date: July 30, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

• Length of stay > 24 hours; Parkinson patients who met Chinese diagnostic criteria for Parkinson's disease (2016 edition) ; willing to participate in the study and able to complete the scale.

Exclusion Criteria:

• Parkinson's disease caused by cerebrovascular disease, Encephalitis, traumatic brain injury; patients who have received whole blood, plasma, albumin within one month; patients with severe gastrointestinal disease, metabolic disease and other wasting diseases; Patients with critical illness, severe cognitive impairment, and inability to communicate.

Related Conditions & MeSH terms

• Malnutrition
• Parkinson Disease

Locations

Country	Name	City	State
China	Second Affiliated Hospital of Medical College of Zhejiang University	Hangzhou	Zhejiang

Sponsors (1)

Lead Sponsor	Collaborator
Second Affiliated Hospital, School of Medicine, Zhejiang University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Incidence rate of nutritional risk Nutrition Assessment	Mini Nutritional Assessment (MNA) score. This scale is used to evaluate the nutritional status .MNA consists of 18 subjects, covering four aspects: anthropometric assessment, general state assessment, recent diet assessment and subjective self-assessment. The total score is 30. Malnutrition is defined as score < 17, critical state of malnutrition is defined as score 17-24, and good nutrition is defined as score > 24.	Within 8 hours after admission