Parkinson Disease Clinical Trial
Official title:
A Comparison Of Home Exercises With Multimodal Real-time Sensory Feedback To The Same Exercise Program With No Enhanced Feedback on Walking Automaticity in People With Parkinson Disease.
People with Parkinson Disease (PWPD) have significant problems with velocity, safety and dual tasking during walking that may be secondary to poor automaticity. Sensory functions, especially visual dependence and proprioceptive integration are critical for efficient walking and are often impaired. This home program compares the use of multimodal sensory feedback during stepping and balance exercises in PWPD to a group without the sensory feedback performing the same basic exercises.
Parkinson disease impairs motor and sensory functions. Automaticity of gait is lost
increasing the use of higher center control of walking, leading to cognitive fatigue, slower
movement and motor errors. People with Parkinson disease (PWPD) improve motor performance
when external sensory cues, which bypass the faulty basal ganglia, are used during
interventions. Enhancing proprioceptive, visual and vestibular cues that are critical for
walking has the potential to improve gait and decrease cognitive fatigue by restoring
automaticity.
This is a single-blinded randomized controlled study with repeated measures to evaluate the
effects of a home exercise program with or without the addition of multi-modal sensory
feedback (MMSF) in real-time on automaticity of gait and balance. PWPDs are randomly assigned
to one of 2 home exercise groups. There are two 6 week exercise sessions with a 6 week of no
exercises inter-spaced between them. The exercises promote rapid and large movement in
stepping activities, balance using self-perturbation through single, leg swings and standing
on a compliant surface for sensory re-weighting. People in the experimental group perform the
program with real-time with MMSF. Participants are to progress exercises in speed and
distance as well as performing with eyes closed to improve proprioceptive processing and
automaticity.
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