Chinese FPD Registry

Parkinson Disease Clinical Trial

Official title: The Chinese Familial Parkinson's Disease Registry

Status Recruiting

Clinical Trial Summary

The purpose of the Chinese Familial Parkinson's disease Registry (CFPDR) is to develop a database of patients with familial Parkinson's disease (PD) in China.

Clinical Trial Description

Parkinson's disease (PD) is the second most common disorder among degenerative neurological disease. Familial PD (FPD) has its unique clinical feature and genetic basis. We aim to establish a database of FPD,and characterize the clinical feature, genetic basis, environmental factors and their interactions FPD in China.

Method:

1. Clinical feature will be measured by scales and neurological tests.Standard scales includes: Unified Parkinson's Disease Rating Scale(UPDRS), Hoehn-Yahr stages, NMSS, MMSE, PDSS(Parkinson disease sleep scales),Rapid Eye Movement Sleep Behaviour Disorder Questionnaire(RBDQ-HK),ESS(Epworth Sleepiness Scale),Rome III functional constipation scale，SCOPA-AUT (the Scale for Outcomes in PD for Autonomic Symptoms)，PFS(Parkinson Fatigue Scale)，CH-RLSq，Hyposmia rating scale(HRS)HAMILT depression scale，the 39-item Parkinson's Disease Questionnaire(PDQ-39)，Freezing of gait scale(FOG)，dyskinesia related scales, Wearing-off scale(WO)

2. Peripheral blood from patients and other members in family will be collected for familial PD genetic testing.

3. The environmental factors are exploded by questionnaires including smoking,drinking, pesticide and heavy metals. ;

Related Conditions & MeSH terms

• Parkinson Disease

• NCT number: NCT03508986
• Study type: Observational
• Source: Xiangya Hospital of Central South University
• Contact: Jifeng Guo, Ph.D.
• Phone: +8613974936815
• Email: guojifeng2003@163.com
• Status: Recruiting
• Start date: February 1, 2017
• Completion date: February 1, 2027