Parkinson Disease Clinical Trial
Official title:
Ultra High Field Magnetic Resonance Imaging as a Biomarker for Premotor Parkinson's Disease
| NCT number | NCT03288909 |
| Other study ID # | eIRB#5611 |
| Secondary ID | |
| Status | Recruiting |
| Phase | |
| First received | |
| Last updated | |
| Start date | September 2015 |
| Est. completion date | January 2021 |
This is a prospective observational study investigating the utility of 7 Tesla MRI to quantify nigrosome1 signal in a cohort of individuals with recent onset Parkinson's disease and in at-risk cohorts at a premotor state of Parkinson's disease.
| Status | Recruiting |
| Enrollment | 18 |
| Est. completion date | January 2021 |
| Est. primary completion date | January 2020 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | All |
| Age group | 18 Years and older |
| Eligibility |
Inclusion Criteria: - Idiopathic Parkinson's disease within 1 year of motor symptom onset. Idiopathic REM sleep behavior disorder without signs/symptoms of Parkinson's disease. Age-matched controls. Exclusion Criteria: - Atypical Parkinsonism - Contraindications for MRI |
| Country | Name | City | State |
|---|---|---|---|
| United States | Oregon Health & Science University | Portland | Oregon |
| Lead Sponsor | Collaborator |
|---|---|
| Oregon Health and Science University |
United States,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Quantitative signal analysis of nigrosome 1 | 1 year | ||
| Secondary | Change in quantitative signal analysis of nigrosome 1 | 3 years |
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