Effect of Computer-based Cognitive Training on Attention and Executive Functions in Patients With Parkinson's Disease

Parkinson Disease Clinical Trial

Official title:

The Effect of Computer-based Cognitive Training on Attention and Executive Functions in Patients With Parkinson's Disease

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03285347
• Other study ID #: H-17000220
• Status: Completed
• Phase: N/A
• Start date: October 1, 2017
• Est. completion date: June 30, 2020

Study information

• Verified date: January 2021
• Source: Bispebjerg Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The current study adresses the effect of two different computer-based cognitive trianing programmes on attention and executive functions in patients with Parkinson's disease.

Description:

The current study adresses the effect of two different computer-based cognitive training programmes (Brain+ Evolution and Scientific Brain Training PRO) on attention and executive functions in patients with Parkinson's disease. The patients are assigned to one of three groups. Two training groups with each their programme, and a control Group. The training groups will train at home for 8 weeks with follow-ups every second week. The control group will not train at home, but will also receive a follow-up with computer-based stimuli (computerized Card game) every second week, to minimize the possibility that a possible effect is due to the follow-up's with a professional, and not due to the computer training at home.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 30
• Est. completion date: June 30, 2020
• Est. primary completion date: February 29, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Patients with Parkinson's disease AND

• Montreal cognitive assesment (MOCA)-score between 22-28

• Motorically cabable of using an iPad

• Not receiving antipsychotic medicine

• No comorbid diseases which might influence the level of executive functioning, for an example ADHD or acquired brain damage

Exclusion Criteria:

• People without Parkinson's disease

• Parkinson's patients not included in the above inclusion criteria

Related Conditions & MeSH terms

• Executive Dysfunction
• Parkinson Disease

Intervention

Device:
• Computer-based cognitive training
Computer-based cognitive programmes are computer programmes designed as games with the aim of training patients in certain cognitive domains.

Locations

Country	Name	City	State
Denmark	Bispebjerg Hospital	Copenhagen	Region Hovedstaden

Sponsors (1)

Lead Sponsor	Collaborator
Bispebjerg Hospital

Country where clinical trial is conducted

Denmark, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	SDMT	Symbol digit modalities test, neuropsychological test of processing speed	2 minutes
Primary	PDQ-39	Parkinson's disease questionnaire; daily functioning and well-being in Parkinson's disease	20 minutes
Secondary	HADS	Hospital anxiety and depression screening	10 minutes
Secondary	Digit span	Digit span Wais-IV; Working memory	10 minutes
Secondary	Verbal fluency	S-Words, animal-names and A/F-words	3 minutes
Secondary	Stroop colour/word test	Stroop colour/Word test, respone inhibition	3 minutes
Secondary	Trail Making A and B	Trail Making A and B, cognitive flexibility	5 minutes