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Neural and Kinematic Features of Freezing of Gait for Adaptive Neurostimulation

Parkinson Disease Clinical Trial

Official title:
Neural and Kinematic Features of Freezing of Gait for Adaptive Neurostimulation

Clinical Trial Summary

Continuous deep brain stimulation (cDBS) is an established therapy for the major motor signs in Parkinson's disease, however some patients find that it does not adequately treat their freezing of gait (FOG). Currently, cDBS is limited to "open-loop" stimulation,without real-time adjustment to the patient's state of activity, fluctuations and types of motor symptoms, medication dosages, or neural markers of the disease. The purpose of this study is to determine if an adaptive DBS system,responding to patient specific, clinically relevant neural or kinematic feedback related to FOG, is more effective than continuous DBS on the motor Unified Parkinson's Disease Rating Scale (UPDRS III) and gait measures of PD.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03180515
Study type Interventional
Source Stanford University
Contact
Status Completed
Phase N/A
Start date May 15, 2017
Completion date October 31, 2018
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