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A Study To Evaluate the Safety and Efficacy of Human Neural Stem Cells for Parkinson's Disease Patient — hNSCPD  

Parkinson Disease Clinical Trial

Official title:
A Single Arm, Open-Label，Pilot Study to Evaluate the Safety and Efficacy of Human Neural Stem Cells Injection (ANGE-S003) Through Nasal Way Delivery to Patients With Parkinson's Disease

Clinical Trial Summary

This Pilot study will evaluate the safety and Efficacy of an investigational cell transplantation therapy, h-NSC, in patients with Parkinson's disease, through nasal drug delivery, a new delivery way. All patients will receive the therapy, which consists of human neural stem cells,

Clinical Trial Description

h-NSC is a cellular therapeutic consisting of human fetal neural stem cells (h-NSC). h-NSC injection will be delivered through nasal way for patients with Parkinson's disease (PD).

The study will enroll 12 moderate to severe PD patients to be treated with the cell injection therapy at the same dose. The total therapy course will be four weeks，one dose for one week. The follow up will be two times within 24 weeks after finishing the treatment. The main objective of the study is to evaluate the efficacy and safety of the cell transplantation by this new delivery way. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03128450
Study type Interventional
Source Second Affiliated Hospital of Soochow University
Contact
Status Enrolling by invitation
Phase Phase 2/Phase 3
Start date April 15, 2017
Completion date November 1, 2018
View Details
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