A Training of the Rhythmic Skills With a Serious Game to Improve Gait and Cognitive Abilities in Parkinson's Disease

Parkinson Disease Clinical Trial

— RGP  

Official title:

Rhythm Game Park: a Training of the Rhythmic Skills With a Serious Game to Improve Gait and Cognitive Abilities in Parkinson's Disease

Clinical Trial Details — Status: Suspended

Administrative data

• NCT number: NCT02855710
• Other study ID #: 9499
• Status: Suspended
• Phase: N/A
• Start date: March 4, 2016
• Est. completion date: January 2022

Study information

• Verified date: December 2021
• Source: University Hospital, Montpellier
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This project aims at assessing the opposite relation, namely the effect of a training of the general timing abilities on gait in Parkinson's disease. Timing rehabilitation will be done by the means of a serious game. Serious games are more and more used to improve the compliance and the efficacy of reeducaiton programs. Overall, we propose to test a low-cost tool for rehabilitation.

Description:

Auditory rythmic cueing is a method consisting in presenting a regular auditory stimulus (metronom or music) when someone is walking. It is known to improve gait in pathologies such as Parkinson's disease. It has also an effect on general timing abilities (e.g. tapping the beat of the music). This project aims at assessing the opposite relation, namely the effect of a training of the general timing abilities on gait in Parkinson's disease. Timing rehabilitation will be done by the means of a serious game. Serious games are more and more used to improve the compliance and the efficacy of reeducaiton programs. Overal, we propose to test a low-cost tool for rehabilitation.

Recruitment information / eligibility

• Status: Suspended
• Enrollment: 35
• Est. completion date: January 2022
• Est. primary completion date: January 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• age < 18
• good understanding of the nature, the goal and the methodology of the study
• signing of the informed consent
• being insured with a social security
• Diagnostic of idiopathic Parkinson's disease following the Queen Square Brain Bank (Hughes, 1992)
• Hoehn et Yahr between 2 and 3
• mild to moderate walk and speech deficits (Item MDS-UPDRS)
• stable therapy one month before inclusion for all the duration of the study

Exclusion Criteria:

• Atypic Parkinson Syndrom (oculomotor troubles, early falls, hallucinations, MoCA<20, early dysautonomy)
• dystonia ou dyskinesia preventing from using a tablet (item MDS-UPDRS4.2 >2)
• Unable to move without help (walking stick, walker, wheelchair) (item MDS-UPDRS 2.12 >2)
• adult protected by law
• deprivation of liberty
• High propability of non compliance to the protocol
• pregnant women, nursing women
• moderate to severe auditory trouble
• Severe walk fluctuations item MDS-UPDRS 4.4 >2)
• Pacemaker or neurosensorial device or heart defebrillator
• Cochlear implants
• ferromagnetic external bodies claose to the brain
• Metallic prothesis
• agitated, non cooperative patient
• claustrophobic patient
• neuro-surgical shunt valves
• dental appliance

Related Conditions & MeSH terms

• Parkinson Disease

Intervention

Other:
• Rhythm workers training Perceptive timing
Perceptive timing training
• Rhythm workers training sensorimotor timing
Sensorimotor timing training
• No Rhythm workers training
No training

Locations

Country	Name	City	State
France	Gui de Chauliac Hospital	Montpellier

Sponsors (4)

Lead Sponsor	Collaborator
University Hospital, Montpellier	Laboratory EUROMOV EA 2991, Laboratory Parole et Langage UMR 7309, Université Montpellier

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Rythmic capacities	Evaluate the effect of the training of the rythmic capacities (Sensorimotor timing abilities) on the walk and the speak	3 months
Secondary	cognitive functions	Evaluate the cognitive functions by Neurospsychologic tests	3 months
Secondary	Mesure of the neural reorganisation	Evaluate the structure et connectivity by MRI	3 months