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Study of Motor Slowing in Parkinson's Disease by a Computerized Mental Chronometry Paradigm — ERAMPPCI  

Parkinson Disease Clinical Trial

Official title:
Study of Motor Slowing in Parkinson's Disease by a Computerized Mental Chronometry Paradigm

Clinical Trial Summary

Action slowing has been demonstrated in many diseases. Parkinson's disease (PD) and Huntington's disease (HD) are two neurodegenerative diseases affecting the basal ganglia, particularly the medial globus pallidus, and the clinical expression of these two diseases is characterized by a combination of motor and cognitive disorders, but with two opposing patterns of dysfunction. Action slowing has been demonstrated in both of these diseases and has been extensively studied in Parkinson's disease, suggesting a perceptive-cognitive origin. Far fewer studies have been conducted in Huntington's disease. However, all of these studies were performed with different methodologies in small cohorts and the value of the proposed study is to use a validated and standardized computerized mental chronometry paradigm, providing a better understanding of the mechanisms of action slowing in these two diseases and to more clearly define a disease-specific profile.

Clinical Trial Description

n/a

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02814201
Study type Observational
Source Centre Hospitalier Universitaire, Amiens
Contact
Status Completed
Phase N/A
Start date July 2011
Completion date November 2016
View Details
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