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Paresis clinical trials

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NCT ID: NCT03600454 Completed - Surgery Clinical Trials

The Effect of Anesthesia on Perioperative Muscle Weakness and Neuro-endocrine Stress Response

MUSCLE
Start date: September 1, 2018
Phase: N/A
Study type: Interventional

The effect of surgery, in contrary to critical illness, on muscle weakness hasn't been thoroughly investigated. Recent data suggest that elective surgery may also induce muscle weakness. The neuro-endocrine stress response could be involved in the pathophysiology. Whether the mode of anesthesia/analgesia can influence muscle weakness, by influencing the neuro-endocrine stress response is unknown. Gaining insight in this matter could affect quality of care and benefit patient recovery and satisfaction.

NCT ID: NCT03592745 Completed - Stroke Clinical Trials

Transcutaneous Vagus Nerve Stimulation (tVNS) and Robotic Training to Improve Arm Function After Stroke

tVNS
Start date: August 9, 2018
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate if multiple therapy sessions of Transcutaneous Vagus Nerve Stimulation (tVNS) combined with robotic arm therapy lead to a greater functional recovery in upper limb mobility after stroke than that provided by robotic arm therapy in a sham stimulation condition.

NCT ID: NCT03588832 Completed - Stroke Clinical Trials

Prevalence of Postural Patterns of Upper Extremity.

Patterns
Start date: June 1, 2018
Phase:
Study type: Observational

A high number of patient with stroke develops spasticity of the upper extremity, this clinical sign of damage of 1 motoneuro (MN), causes postures and patterns of abnormal movement, due to the hyperexcitability of the MN and the rheological alterations that occur in the affected muscles. These alterations limit the use of upper extremity, restricting its use in functional activities and affecting the quality of life and social participation of the users. During the last few years the classification of the Hefter patterns for spasticity of the upper limb was created, with the end of having a common language and orienting the current therapeutic strategies oriented towards the arm. Objective: To determine the prevalence of patterns and their impact on the quality of life of patients after a stroke. Material and method: Descriptive design of cross section, the sample will be composed of 600 people who attend integral rehabilitation center of regions V, VIII, IX and X in Chile, that meet the inclusion criteria and sign the informed consent. The study will include a measurement made by a trained professional from each participating center using a registration form, the FIM scale and the Barthel index, to assess quality of life. Results: It will be analyzed with the SPSS software through descriptive and inferential statistics considering the nature of the variables, all the analyzes will consider as statistically significant the results with p values less than or equal to 0.05. Depending on the interval or ordinal level of the measurements, the coefficients r of Pearson and rho of Spearman will be used to calculate the correlations. Applicability: The results will determine the prevalence in this geographical sector, disseminate this classification and promote the use of a common language among professionals to enhance their daily work. In addition, it will allow to determine how the affectation of the upper extremity through the identification of a certain pattern alters the quality of life of the patient. This new information can be a fundamental input in the generation of future studies that seek to guide in relation to the use of therapeutic strategies in these people.

NCT ID: NCT03586440 Completed - Muscle Weakness Clinical Trials

Effect of Forward Head and Rounded Shoulder Posture on Hand Grip Strength in Asymptomatic Young Adults

FHRSP-RS-FHP
Start date: May 3, 2018
Phase:
Study type: Observational

- see if there is significant difference between subjects with forward head rounded shoulder posture and subjects with normal posture in hand grip strength in asymptomatic young adults - see if there is significant difference between subjects with rounded shoulder posture and subjects with normal posture in hand grip strength in asymptomatic young adults

NCT ID: NCT03581760 Completed - Muscle Weakness Clinical Trials

Cycling Exercise in Mechanical Ventilation

Start date: May 2, 2017
Phase: N/A
Study type: Interventional

Prolonged critical illness renders survivors with increased long-term morbidity associated with high healthcare costs. Muscle weakness and fatigue are reported as the main contributors to long-term poor functional outcomes. Emerging evidence for early mobilisation demonstrates reduction in the number of ventilator days and hospital length of stay. It has been demonstrated that daytime motoring (passive and active) can improve functional capacity in intensive care patients. The aim of the proposed study is to evaluate the effect of cycling exercise in patients on mechanical ventilation appointed to weaning process.

NCT ID: NCT03567122 Completed - Muscle Weakness Clinical Trials

Attentional Focus Influence During Cranio-Cervical Flexion Test

Start date: August 1, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to termine if a different attentional focus would alter the motor control in cervical muscles during the cranio-cervical test.

NCT ID: NCT03555825 Completed - Hemiplegia Clinical Trials

Burke-Hocoma Efficiency Study

Start date: May 1, 2016
Phase: Phase 3
Study type: Interventional

The ArmeoSpring device is an exoskeleton (3 joints and 6 degrees of freedom) with integrated springs. The investigators hypothesize that 3 days of training for 6 weeks with the Hocoma Armeo Spring device will be efficient and more effective than one on one ArmeoSpring therapy.

NCT ID: NCT03549975 Completed - Stroke Clinical Trials

Hand Rehabilitation Using Botulinum Toxin and Functional Electrical Stimulation-pilot Study

Start date: May 18, 2016
Phase: Phase 4
Study type: Interventional

The investigator tried to find out possibility of functional improvement using botulinum toxin injection targeting finger flexor spasticity with functional electrical stimulation among chronic stroke patients who did not show any improvement in hand function.

NCT ID: NCT03528018 Completed - Stroke Clinical Trials

Efficacy of a Combined Transcranial Direct Current Stimulation and Virtual Reality Intervention

REACT01
Start date: June 1, 2015
Phase: N/A
Study type: Interventional

Rehabilitation options for stroke survivors who present severe hemiparesis in chronic stages are limited and may end in compensation techniques that involve the use of the less affected arm to achieve some degree of functional independence. Transcranial direct current stimulation (tDCS) is a non-invasive technique that has been used after stroke to promote excitability of the surviving neural architecture in order to support functional recovery. Interestingly, cortical excitability has been reported to increase when tDCS is combined with virtual reality. This synergetic effect could explain the promising results achieved by preliminary experimental interventions that combined both approaches on upper limb rehabilitation after stroke. The objective of this study is to explore the use of these interventions in subjects with severe hemiparesis and to determine its efficacy in comparison to conventional physical therapy

NCT ID: NCT03526211 Completed - Muscle Weakness Clinical Trials

Safety Evaluation of Functional Electrical Stimulation (FES) Cycling in Intensive Care Unit Patients

FES Cycling
Start date: July 24, 2018
Phase: N/A
Study type: Interventional

Intensive care unit acquired muscle weakness (ICUAW), is a common disease which influence rehabilitation, extend mechanical ventilation and length of stay in intensive care unit, and affect quality of life at hospital discharge. To prevent ICUAW, different strategies of early mobilization are recommended. But all cannot be applied in all ICU patients. Some of them benefit from heavy therapies like circulatory assistance or renal replacement therapy for example, that limit mobilization. Cycloergometer is a tool that allows continuous passive mobilization in bedridden and even unconscious patients. Neuromuscular electrical stimulation (NMES) is an alternative that helps preserve muscle mass and limit muscle atrophy. Early bedside cycle exercise coupled with NMES is an interesting new approach where application of an electrical stimulation along specific motor nerves on each lower limb, generates muscles contractions and pedaling on cycloergometer. The aim of this study is to evaluate safety and feasibility of this coupled technique called Functional Electrical Stimulation (FES) Cycling, in ICU patients.