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Paralysis clinical trials

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NCT ID: NCT03016923 Completed - Cerebral Palsy Clinical Trials

Functional Electrical Stimulation (FES) for Upper Extremity Hemiplegia in Children With Cerebral Palsy

Start date: March 2016
Phase: N/A
Study type: Interventional

The proposed pilot study seeks to explore the effectiveness of Functional Electrical Stimulation (FES) to improve upper limb function in children and youth (aged 6 to 18 years) with hemiplegic cerebral palsy, as measured by the QUEST grasp score and other secondary outcome measures obtained pre- and post-intervention in a case series study design.

NCT ID: NCT03006783 Completed - Facial Palsy Clinical Trials

Assessment of the Cross-face Nerve Graft in the Treatment of Facial Paralysis

Start date: March 2016
Phase: N/A
Study type: Observational

A retrospective and cross-sectional analysis of standard of care for facial paralysis involving the cross-face nerve graft in the past 20 years. - Imagery analysis - Questionnaires

NCT ID: NCT03005938 Completed - Clinical trials for Cerebral Palsy, Spastic

Influence of the Spinal Manipulation on Muscle Spasticity and Manual Dexterity in Cerebral Palsy.

SpiManCP
Start date: September 2016
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate a short term influence of the Spinal Manipulation (SM) on the wrist muscles spasticity and manual dexterity in children with spastic Cerebral Palsy. Effect of SM and imitation of the SM has to be compared in the double-blinded randomized clinical trial.

NCT ID: NCT03002285 Completed - Cerebral Palsy Clinical Trials

Fitts Law in People With Cerebral Palsy

Start date: January 2016
Phase: N/A
Study type: Interventional

Introduction: Cerebral palsy (CP) is a non-progressive disorder in the brain which makes the control and execution of movements difficult. One of the possible ways to analyze motor control in these individuals could be through analysis of movement speed and accuracy. Objective: To verify the speed-accuracy trade-off in individuals with CP. Method: 96 individuals were evaluated, 48 with CP and 48 with typical development (TD), matched by age and sex. The software used was the "Fitts' Reciprocal Aiming Task v.1.0 (Horizontal)", performed on a computer using an external optical mouse, with progressive indices of difficulty (IDs): ID2, ID4a and ID4b. Each index of difficulty was performed three times and the total time/touches captured.

NCT ID: NCT02998281 Completed - Cerebral Palsy Clinical Trials

Effects of Inspiratory Muscle Training in Children With Cerebral Palsy

Start date: December 2016
Phase: N/A
Study type: Interventional

Even if cerebral palsy not directly effect respiratory system, impairment of nervous and muscle systems, because of the brain damage, may cause respiratory functions impairment. In literature, it has been showed that children with cerebral palsy have decreased respiratory muscle strength and associated with trunk control, quality of life and respiratory functions. But, there is no study in literature that aims to increase respiratory muscle strength in these children. Hence, the aim of this study is to investigate effects of inspiratory muscle training on respiratory functions, trunk control, activities of daily living, functional exercise capacity and quality of life in children with cerebral palsy.

NCT ID: NCT02988856 Completed - Blepharoptosis Clinical Trials

Magnetic Correction of Eye Lid Paralysis

Start date: July 1, 2015
Phase: N/A
Study type: Interventional

Objective 1: Determine the safety and feasibility of externally mounted magnets for extended management of chronic eyelid movement disorders by measuring visual acuity and corneal and skin integrity and comfort over 8 weeks of wear. Objective 2: Collect preliminary data on the relative efficacy of external magnetic devices by comparing them to externally mounted lid weights and ptosis crutches using rating scales and video analysis of blink biomechanics.

NCT ID: NCT02984735 Completed - Cerebral Palsy Clinical Trials

Chewing Performance Level and Gross Motor Function in Children With Cerebral Palsy

Start date: January 2016
Phase:
Study type: Observational

The purpose of this study is to determine the association between gross motor function and chewing performance level in children with cerebral palsy (CP). A cross-sectional study was conducted in 152 children (ages 2-10y, 51.3% male) with a diagnosis of spastic CP. The Gross Motor Function Classification System (GMFCS) was used to determine gross motor function levels of children. Chewing performance level was determined by using the Karaduman Chewing Performance Scale (KCPS).

NCT ID: NCT02977286 Terminated - Constipation Clinical Trials

Naloxegol to Prevent Lower Gastrointestinal Paralysis in Critically Ill Adults Administered Opioids

Start date: January 1, 2017
Phase: Phase 4
Study type: Interventional

This study evaluates the addition of naloxegol (Movantik) to a laxative protocol in critically ill adults requiring scheduled opioid (e.g. fentanyl) therapy. Half of the participants will receive naloxegol and a laxative protocol and half the participants will receive a placebo and a laxative protocol.

NCT ID: NCT02973152 Completed - Clinical trials for Vocal Cord Paralysis Unilateral

Laryngeal Reinnervation Versus Thyroplasty in Patients With Vocal Fold Weakness.

VOCALIST
Start date: May 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to help determine the most effective treatment for participants with Unilateral Vocal Fold Paralysis. There are currently two types of operations used to treat this condition. One operation is called thyroplasty. Doctors place a small piece of safe plastic into the side of the participant's voice box to push the weak vocal cord into a position to enable better speech and swallowing. In the other operation called laryngeal reinnervation, doctors repair the neck nerve supply to the vocal cord using parts of other unaffected nerves to enable better speech and swallowing. The investigators do not know which of these methods is better and are conducting this study to start comparing the two operations so that a larger clinical trial can be conducted in the future to tell us which operation is best.

NCT ID: NCT02969993 Completed - Laryngeal Paralysis Clinical Trials

Very Long Term VHI Voice Outcome After MTIS

Start date: December 2016
Phase: N/A
Study type: Interventional

Long term assesment of voice outcome after Montgomery Thyroplastie by performing a Survey of operated patients using the voice handicap index scale