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Paralysis clinical trials

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NCT ID: NCT03727217 Completed - Thyroidectomy Clinical Trials

Performance of Ultrasound in the Early Diagnosis of Vocal Cords Paralysis

PECV
Start date: July 10, 2018
Phase: N/A
Study type: Interventional

Thyroid and parathyroid surgery concerns around 50 000 patients a year in France. One of its main complications is paralysis of vocal cords, and the consequences can be serious. In this study, the main gold is to evaluate diagnostic performances of ultrasound for an early diagnosis (as soon as awakening of the patient) of vocal cords paralysis in the post-operative period in order to prevent at best complications.

NCT ID: NCT03712072 Active, not recruiting - Cerebral Palsy Clinical Trials

Multi-modal Neuroimaging in Children With Cerebral Palsy or Brachial Plexus Birth Palsy

Start date: February 1, 2018
Phase:
Study type: Observational

The main goal of this study is to identify abnormal functional and anatomical brain reorganization associated with hand, foot, and shoulder function in children (0-18 years old) with cerebral palsy (CP) due to periventricular white matter injury (PV-WMI) or brachial plexus birth palsy (BPBP) using a multi-modal neuroimaging approach.

NCT ID: NCT03710343 Active, not recruiting - Cerebral Palsy Clinical Trials

Metformin for Motor and Cognitive Improvement in Children With Cerebral Palsy: A Feasibility Study

Start date: November 14, 2023
Phase: Phase 2
Study type: Interventional

The study design is a single-subject ABA clinical trial that is investigating the feasibility including adherence, safety and tolerability of metformin in children aged 5 to 18 years with cerebral palsy (CP). ABA refers to Phase A1 with no metformin, Phase B with metformin, and Phase A2 with no metformin. Secondarily, the study is exploring whether metformin has possible health benefits for improving motor function and cognition.

NCT ID: NCT03692494 Not yet recruiting - Dysphonia Clinical Trials

The Effects of Adding Expiratory Muscle Strength Training in Voice Therapy

Start date: September 1, 2024
Phase: N/A
Study type: Interventional

Evaluate if adding expiratory muscle strength training to traditional voice therapy for individuals with dysphonia due to glottal insufficiency improves maximal expiratory pressure, acoustic and aerodynamic measures (i.e. amplitude, maximum phonation time, peak expiratory flow), and voice related quality of life.

NCT ID: NCT03691506 Completed - Clinical trials for Hemiplegic Cerebral Palsy

Comparison of CIMT and Its Modified Form on Upper Motor Function Outcomes in Hemiplegic Cerebral Palsy.

CIMT
Start date: October 15, 2018
Phase: N/A
Study type: Interventional

The aim of this research is to compare the effect of classic constraint-induced movement therapy and its modified form on upper extremity motor function outcomes and psychosocial impact in hemiplegic cerebral palsy. Randomized controlled trials with 2-3 weeks follow-up. The sample size is 40. The subjects are divided in two groups, 20 subjects in classical CIMT group and 20 in modified CIMT group. Study duration is of 6 months. Sampling technique applied will be purposive non probability sampling technique. Only 4-12 years individual with hemiplegic cerebral palsy are included. Tools used in the study are Box and Block test, Cerebral palsy (quality of life), Kid Screen 27 and QUEST (quality of upper extremity skill test). Data will be analyzed through SPSS 21.

NCT ID: NCT03677778 Completed - Anesthesia, Local Clinical Trials

Interscalene Brachial Plexus Block Washout to Reverse Inadvertent Phrenic Nerve Blockade

Start date: October 22, 2018
Phase: N/A
Study type: Interventional

One of the most frequently performed peripheral nerve blocks (the injection of local anesthetic near nerves to block sensation/ movement to a specific part of the body) is the interscalene brachial plexus block for upper extremity surgeries. This type of block can unmask underlying respiratory issues such as shortness of breath due to a well-known and typically insignificant side effect of temporary diaphragmatic paralysis. The nerve block may be able to use saline solution to wash out the local anesthetic and potentially reverse this respiratory side effect. Specifically, the goal of this study is to determine if the injection of saline through the nerve block catheter reverses blockade of the phrenic nerve supplying the diaphragm, without affecting the ability of the nerve block to provide pain control after surgery.

NCT ID: NCT03668548 Enrolling by invitation - Cerebral Palsy Clinical Trials

10-week Leucine Supplementation in Cerebral Palsy

Start date: August 20, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the effects of 10-weeks leucine supplementation on muscle growth, metabolism, body composition, inflammation and wellbeing in adolescents and young adults with CP.

NCT ID: NCT03662139 Completed - Cerebral Palsy Clinical Trials

Dynamic Gait Index in Hemiplegic Cerebral Palsy

Start date: April 1, 2018
Phase:
Study type: Observational

The purpose of this study is to assess validity and reliability of Dynamic Gait Index (DGI) in patients with unilateral spastic cerebral palsy

NCT ID: NCT03653494 Enrolling by invitation - Clinical trials for Phrenic Nerve Paralysis

the Clinicaltrail of the Effection Which of Phrenic Block Using in Non-intubated Video-assisted Thoracoscopic Surgery

Start date: October 1, 2018
Phase: Early Phase 1
Study type: Interventional

Putting 80 patients divided into group S(non-intubated general anesthesia combine with Paravertebral blocks、surface spray anesthesia and Vagus block) and group D(non-intubated general anesthesia combine with Paravertebral blocks、surface spray anesthesia、Vagus block and Phrenic block)randomly,compare the volume of anesthetic and the number of increasing anesthetic during operation were compared between the two groups.If the date of group S greater than group D,it shows that the effect of anesthetic effect of group D is better than group S.

NCT ID: NCT03651063 Completed - Clinical trials for Upper Extremity Paralysis

Socially Assistive Robot in Upper-Limb Neurorehabilitation

Start date: May 10, 2019
Phase: N/A
Study type: Interventional

30 one year post stroke patients with upper limb paresis will be recruited to this study. The study is an RCT consists of two groups of intervention: 1. social robot, 2. computer, and one control group with no intervention. the intervention consists of 15 therapy sessions of reach-to-grasp games of the affected upper limb.