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Paralysis clinical trials

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NCT ID: NCT04247412 Recruiting - Vocal Polyp Clinical Trials

Laryngomicrosurgery Under NIDP General Anesthesia Supported by THRIVE

NIDP
Start date: April 20, 2020
Phase:
Study type: Observational

Laryngomicrosurgery requires deep paralysis and general anesthesia to finish the procedure. After the procedure, patients need a long time to recover. In the present study, with the support of the transnasal humidified rapid-insufflation ventilatory exchange, laryngomicrosurgery would be finished under nonintubated deep paralysis (NIDP) general anesthesia. In this case series study, the investigators will test the safety and feasibility of such a technique.

NCT ID: NCT04243590 Completed - Cerebral Palsy Clinical Trials

Turkish Version of Hand-Use-at-Home Questionnaire

Start date: February 1, 2020
Phase:
Study type: Observational

To investigate the validity and reliability of the Turkish Version of parent-rated Hand-Use-at- Home questionnaire (HUH) in children with neonatal brachial plexus palsy or unilateral cerebral palsy.

NCT ID: NCT04243408 Recruiting - Cerebral Palsy Clinical Trials

Treatment of Children With Cerebral Palsy With Autologous Umbilical Cord Blood, a Pilot Study

Start date: July 8, 2020
Phase: Phase 2
Study type: Interventional

This study is a phase II, prospective, double blind, placebo-controlled study of the efficacy of autologous umbilical cord blood infusion. The study population will consist of 72 children ages 2 months to 12 years with cerebral palsy. The population will be randomly assigned to 2 groups, 36 children in each group. The study group be treated by cord blood in the beginning of the study and the control group by placebo product. The study population will be stratified to reduce variance 3 groups by age: 2-12 months / 1-6 years / 6-12 years The study will consist of 4 stages Stage 1: initial assessment by physiotherapist and occupational therapist / treatment by cord blood or placebo / blood work before and after treatment Stage 2: at stage 1 + 3 months assessment by physiotherapist and occupational therapist Stage 3: at stage 1 + 6 months assessment by physiotherapist and occupational therapist / cross-over treatment by cord blood or placebo / blood work before and after treatment Stage 4: at stage 1 + 12 months assessment by physiotherapist and occupational therapist The primary outcome is improvement motor skills six months after treatment at stage 3

NCT ID: NCT04231227 Completed - Cerebral Palsy Clinical Trials

The Validity and Reliability of the Turkish Version of TASC and the Relationship Between SMC and Motor Functions

Start date: July 1, 2018
Phase:
Study type: Observational

Selective motor control (SMC) impairment in children with cerebral palsy (CP) includes movement patterns dominated by flexor or extensor synergy affecting functional movements. The research was designed to investigate the validity and the reliability of the Turkish version of the Test of Arm Selective Control (TASC) (which is improved to evaluate SMC in children with spastic CP) and in order to provide more understanding of the relationship between SMC and upper extremity and gross motor functions. The study included 21 hemiplegic, 11 diplegic and 4 quadriplegic children with CP whose ages are 4 to 18 years and Gross Motor Function Classification System (GMFCS) level changes from 1 to 4, and their parents. In order to evaluate the gross motor function of children, GMFCS and the ability to hold objects with their hands in daily activities were evaluated with Manual Ability Classification System (MACS). ABILHAND-Kids scale was applied to evaluate upper extremity performance. TASC scale was used to evaluate the upper extremity SMC of children.

NCT ID: NCT04227262 Active, not recruiting - Clinical trials for HEMIPLEGIC CEREBRAL PALSY

Efficacy of Lower Extremity Mirror Therapy on Balance in Children With Hemiplegic Cerebral Palsy

Start date: December 1, 2019
Phase: N/A
Study type: Interventional

The study will be conducted to assess the efficacy of mirror therapy on balance in children with hemiplegic cerebral palsy.

NCT ID: NCT04225546 Not yet recruiting - Clinical trials for Cerebral Palsy, Spastic

Sit to Stand Movement in Children With Cerebral Palsy

Start date: January 4, 2020
Phase:
Study type: Observational [Patient Registry]

The aim of this study is to examine the relationship between trunk control and lower extremity selective motor control during the movement of sit to stand (STS) in children with cerebral palsy (CP).

NCT ID: NCT04222049 Completed - Cerebral Palsy Clinical Trials

Application of Vibration Wave Therapy to the Children Suffering From Cerebral Palsy and Tongue Spastic Dysarthria

Start date: July 15, 2019
Phase: N/A
Study type: Interventional

Vibration therapy is the widely used in many neurological disorders for different type of problems. Recently, it is being used by researchers for the betterment of motor disorders and muscle movements of the cerebral palsy patients and significant results are obtained. Investigators are conducting this research to explore that whether this therapy can have some effect on the Spastic Tongue Dysarthria of the Cerebral Palsy patients.

NCT ID: NCT04215562 Enrolling by invitation - Facial Paralysis Clinical Trials

Outcome of Facial Palsy Following Rehabilitation

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

Retrospective case series,the aim of this study is to assess the outcome and rate of complications in patients with facial palsy following rehabilitation, a retrospective study.

NCT ID: NCT04209504 Recruiting - Shoulder Pain Clinical Trials

Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block

Start date: October 12, 2021
Phase:
Study type: Observational

This prospective observational study aims to evaluate the incidence of hemidiaphragmatic paralysis in patients receiving interscalene brachial plexus nerve block with prolonged neural blockade. English speaking American Society of Anesthesiologists (ASA) 1-3 patients ages 18-80 receiving prolonged interscalene nerve block will be randomized into 3 groups: first group receiving a perineural catheter infusing 0.2% ropivacaine; the second group receiving a single shot injection of 10mL liposomal bupivacaine (Exparel; n=20) plus 5 mL 0.5% bupivacaine and the third receiving 20mL liposomal bupivacaine plus 5mL bupivacaine (to be determined by the attending anesthesiologist).Primary outcome will be incidence of hemidiaphragmatic paralysis postoperative day 1 as measured by point of care (POCUS) ultrasound.

NCT ID: NCT04194385 Recruiting - Shoulder Pain Clinical Trials

Upper Trunk Block Versus Costoclavicular Block For Arthroscopic Shoulder Surgery

Start date: May 10, 2020
Phase: N/A
Study type: Interventional

Interscalene brachial plexus block is known as the gold standard for analgesia after shoulder surgery, but limits the use of ipsilateral phrenic nerve paralysis. Recently, interest in potential diaphragm-sparing alternative blocks has increased for patients undergoing shoulder surgery.Two of these blocks are upper trunk block (UTB) and costoclavicular brachial plexus (CCBPB) block. This randomized controlled trial will compare ultrasound-guided UTB and CCBPB in patients undergoing arthroscopic shoulder surgery. The main outcome is pain intensity score at 30 minutes after arrival in the post anesthesia care unit (PACU) as measured by a numerical rating scale (NRS) from 0 to 10. The investigators research hypothesis is that UTB and CCBPB will result in equivalent postoperative analgesia at 30 minutes in the PACU.