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Paralysis clinical trials

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NCT ID: NCT05436782 Recruiting - Stroke; Paralysis Clinical Trials

Effects of Core Strengthening and PNF Pattern on Balance and Plantar Pressure in Chronic Stroke

PNF
Start date: December 3, 2021
Phase: N/A
Study type: Interventional

To compare the effects of core strengthening and PNF on standing balance and plantar pressure in chronic stroke patients

NCT ID: NCT05415514 Recruiting - Paralysis Clinical Trials

Feasibility Study of the Instrumented Evaluation of Eccentric Strengthening in Paresis Patients

RE PAR EX
Start date: December 1, 2022
Phase: N/A
Study type: Interventional

he aim of the "RE PAR EX" research is to evaluate the feasibility of the instrumented examination of the effects of eccentric muscle strengthening in paralytic patients. This project is part of the research axis of the movement analysis laboratory. Following a stroke or spinal cord injury, patients develop a spastic paresis syndrome, which is characterized by the appearance of paresis, musculo-tendinous retractions and muscular hyperactivities. If the traditional treatments proposed (stretching, motor work) show limits, the use of eccentric muscle strengthening in paresis patients has been developing for about ten years, with results superior to the usual treatments. The results of the studies evaluating it are focused on clinical evaluations and do not make it possible to identify the precise origin of the observed responses. A pathophysiological understanding of the therapeutic effects of eccentric strengthening would be possible through instrumented examination of muscle structure and function, combining dynamometry, ultrasound, elastrography and electromyography (EMG). However, the feasibility of this quantified instrumental examination in paretic patients during a strengthening protocol has not been evaluated. The feasibility of a quantified instrumented examination in this setting is the aim of this research, a necessary prerequisite for a larger interventional study to evaluate the biomechanical and neurophysiological effects of eccentric muscle strengthening in paretic patients.

NCT ID: NCT05412485 Not yet recruiting - Clinical trials for Cerebral Palsy Spastic Diplegia

Gait Improvement After Increased Frequency of Robot-assisted Gait Training in Cerebral Palsy Children

Start date: June 7, 2022
Phase: N/A
Study type: Interventional

Robot-assisted gait training (RAGT) can provide a longer training duration with a higher repetition of stepping while maintaining a stable pattern of movement. However, the existing evidence of its effectiveness is not clear. The aim of this study is to investigate the feasibility and the effect of increased frequency (4 times per week) of RAGT compared to the most common frequency (2 times per week). we hypothesize that increased frequency of RAGT will result in greater improvements on the gait functions. This research will investigate the effect of increased frequency on robotic assisted gait training (RAGT) in a frequency of 4 times per a week, and will compare the effect of robotic assisted gait training (RAGT) with increased frequency and with usual frequency (2 times per a week) in regards with gait functional parameters such as balance, speed, endurance, and quality of gait among cerebral palsy (CP) children's.

NCT ID: NCT05403034 Recruiting - Clinical trials for Obstetrical Brachial Plexus Palsy

Study of the Biological Function of Muscle Satellite Cells From Patients With Obstetric Brachial Plexus Palsy

SCOPE
Start date: October 17, 2022
Phase: N/A
Study type: Interventional

The purpose of this prospective work is to study the consequences of obstetrical brachial plexus paralysis on the rotator muscles of the shoulder. The hypothesis is that shoulder stiffness of these children is due to an impairment of the shoulder rotator muscles. The investigators want to test the regenerative capacities of these muscles. The development of a cellular model of this pathology will allow to test new therapeutic perspectives and to validate our hypothesis.

NCT ID: NCT05388422 Completed - Clinical trials for Cerebral Palsy, Spastic

Application of 3D Scanner to Measure Physical Size in Patients With Severe Cerebral Palsy

Start date: June 2, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to improve the manufacturing techniques of hip brace in preventing progressive hip displacement in patients with severe cerebral palsy, through the measurement of patient's physical size using a 3D scanner.

NCT ID: NCT05380011 Completed - Clinical trials for Hemiplegic Cerebral Palsy

Bimanual Task Training and Constraint-Induced Movement Therapy in Hemiplegic Cerebral Palsy Children

Start date: May 20, 2022
Phase: N/A
Study type: Interventional

Various studies have been done comparing the individual effects of the two interventions of Constraint-Induced Movement Therapy and Bimanual Task Training in Hemiplegic Cerebral Palsy Children, but this study will compare the effects of combined interventions with a single intervention. This study will contribute to the upper motor function in hemiplegic cerebral palsy children i.e. manual dexterity, grasp and release function, quality and efficacy of movement, combined bimanual use of both hands and coordination, as a result of two intervention protocols.

NCT ID: NCT05368922 Recruiting - Cerebral Palsy Clinical Trials

Upper Limb Rehabilitation Using Virtual Reality in Children With Cerebral Palsy (RV-REEDUC)

RV-REEDUC
Start date: March 4, 2022
Phase: N/A
Study type: Interventional

This study aims to evaluate the effect of a virtual reality rehabilitation protocol on visuo-motor coordination and upper limb functional abilities in children with unilateral or bilateral cerebral palsy.

NCT ID: NCT05358028 Not yet recruiting - Clinical trials for Hemiplegic Cerebral Palsy

Effect of Hand Arm Bimanual Intensive Technique Including Lower Extremity (HABIT-IL) on Hemiplegic Cerebral Palsy

Start date: May 15, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to determine the functional status of upper extremity using HABIT & HABIT-ILE. And to compare the effects of HABIT with and without lower extremity technique on functional status of hemiplegic cerebral palsy

NCT ID: NCT05355883 Recruiting - Clinical trials for Hemiplegic Cerebral Palsy

Remote Ischemic Conditioning, Bimanual Skill Learning, and Corticospinal Excitability

Start date: December 18, 2021
Phase: Phase 2
Study type: Interventional

Unilateral cerebral palsy (UCP) is a leading cause of childhood disability. An early brain injury impairs the upper extremity function, bimanual coordination, and impacts the child's independence. The existing therapeutic interventions have higher training doses and modest effect sizes. Thus, there is a critical need to find an effective priming agent to enhance bimanual skill learning in children with UCP. This study aims to determine the effects of a novel priming agent, remote ischemic conditioning (RIC), when paired with intensive bimanual skill training to enhance bimanual skill learning and to augment skill dependent plasticity in children with UCP.

NCT ID: NCT05352607 Completed - Cerebral Palsy Clinical Trials

Effect of Transcutaneous Electrical Nerve Stimulation (TENS) on Spasticity in Adult Patients With Spastic Cerebral Palsy

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

Background: Cerebral palsy (CP) is a neurodevelopmental disorder caused by damage of the developing brain and marked by impairments such as increased muscle tone. Physical therapy (PT) is an important element for spasticity management include some modalities as transcutaneous electrical nerve stimulation (TENS). Purpose: To determine the effect of TENS on inhibition of upper limb spasticity in adult patients with spastic cerebral palsy. Methods: Twenty-four adult spastic CP patients aged from 18 to 45 years old with grade 2 to 3 spasticity according to Modified Ashworth Scale will be randomly assigned into two equal groups: TENS group and conventional therapy group. Both groups will receive conventional therapy, while TENS group in addition will receive TENS over elbow flexors with parameter setup of (pulse frequency= 100 Hz, pulse duration= 250 μs, time=30 mints) 3 sessions per week for successive 4 weeks. Outcome measures: Modified Ashworth scale for the spasticity and digital goniometer for elbow joint range of motion, Barthel index scale for upper limb activity of daily living. Follow-up measures will be calculated three times (preintervention, post 2 weeks, and post 4 weeks).