Pain Clinical Trial
Official title:
Impact of Ultrasound- Guided Continuous Retro Laminar Block Versus Continuous Erector Spinae Plane Block on Incentive Spirometry Volumes and Pain Scores in Multiple Rib Fractures
The aim of this study is to compare the incentive spirometry volume and analgesic efficacy of ultrasound guided continuous Retrolaminar block and continuous Erector spinae plain block in patients with multiple rib fractures.
Status | Recruiting |
Enrollment | 60 |
Est. completion date | April 1, 2024 |
Est. primary completion date | April 1, 2024 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 65 Years |
Eligibility | Inclusion Criteria: - Age from 18 to 65 years old. - Both sexes. - Patients with unilateral multiple traumatic rib fractures (= 3 ribs). Exclusion Criteria: - 1st ken refusal. - Patients with any contraindication for regional block as: - Bleeding disorders. - Infection at the injection site. - Patients with hemodynamic instability. - Patients with known hypersensitivity to the study drugs - Unconscious patients - Patients with significant trauma outside the chest wall e.g., acute spine or pelvic fracture, severe traumatic brain or spinal cord injury, or abdominal visceral injuries - Patients with significant lung contusions, pneumothorax, flail chest - Chronic opioid users. - Uncooperative patients and patients with psychiatric illness |
Country | Name | City | State |
---|---|---|---|
Egypt | Tanta University | Tanta | El-Gharbia |
Lead Sponsor | Collaborator |
---|---|
Tanta University |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Maximum inspired volume | Maximum inspired volume will be measure by incentive spirometry which indicate less pain.
Inspiratory capacity (IC) measured by Incentive Spirometry before the block, 30 minutes, 60 minutes after the blocks and then every six hours for subsequent 4 days. |
4 days after intervention. | |
Secondary | Daily and total rescue analgesics consumption. | Need for rescue analgesia and the total consumption of morphine in the form of incremental doses (0.05mg /kg) if Visual Analogue Score (VAS) =4 Pain score will be measured by Visual Analogue Score (VAS) from 0 to 10. Where 0: no pain, 10: the worst pain | 24 hours after intervention. | |
Secondary | Intensive care length of stay. | Time from admission till Intensive care discharge | 28 days after intervention | |
Secondary | Hospital length of stay. | Time from admission till Hospital discharge | 28 days after intervention | |
Secondary | pH | pH will be measure before the block ,6 hours after the block and then daily for subsequent 4 days. | 4 days after intervention. | |
Secondary | PaO2 | PaO2 will be measure before the block ,6 hours after the block and then daily for subsequent 4 days. | 4 days after intervention. | |
Secondary | PaCo2 | PaCo2 will be measure before the block ,6 hours after the block and then daily for subsequent 4 days. | 4 days after intervention. | |
Secondary | FiO2 | FiO2 will be measure before the block ,6 hours after the block and then daily for subsequent 4 days. | 4 days after intervention. | |
Secondary | Respiratory rate | Respiratory rate will be measure before the block ,6 hours after the block and then daily for subsequent 4 days. | 4 days after intervention. | |
Secondary | Adverse effects and complications. | Adverse effects and complications such as hypotension, complications related to catheter insertion, pneumothorax, local anesthetic toxicity, and respiratory depression | 4 days after intervention. |
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