Pain Clinical Trial
Official title:
Comparison of Analgesic Efficacy of Dexketoprofen and Ibuprofen in Long Bone Fractures: Randomised Controlled Double-blind Study
The aim of this study was to compare the efficacy of ibuprofen and dexketoprofen, two common analgesic drugs used in pain control in patients with long bone fractures.
Status | Recruiting |
Enrollment | 100 |
Est. completion date | September 1, 2024 |
Est. primary completion date | September 1, 2024 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 80 Years |
Eligibility | Inclusion Criteria: - over 18 years - Patients under 80 years of age - Patients who agreed to participate in the study - One of the tibia, femur and humerus bones is broken - Patients with a VAS score of 50 and above - Patients with no other injuries requiring emergency surgery - Previously known adverse reactions to the active ingredient of the drugs to be used patients with no history - Conscious patients - Oriented cooperative patients Exclusion Criteria: - Patients under the age of 18 and over the age of 80 - Patients who did not agree to participate in the study - Patients with vital signs outside the normal limits - Patients with a history of adverse reactions to known NSAIDs - Those who cannot determine the severity of pain on the VAS - Patients with a VAS Score of 50 mm or less - Those with other orthopedic injuries pregnant women - Those with advanced systemic disease - Those with malignancy - Those with chronic liver and kidney disease - Those who use neuro-psychiatric drugs with sedative and analgesic effects - Those with a history of psychological and neurological diseases - Patients using analgesics 8 hours before the examination |
Country | Name | City | State |
---|---|---|---|
Turkey | Ankara Bilkent Sehir Hastanesi | Ankara |
Lead Sponsor | Collaborator |
---|---|
Ankara City Hospital Bilkent |
Turkey,
Friday JH, Kanegaye JT, McCaslin I, Zheng A, Harley JR. Ibuprofen provides analgesia equivalent to acetaminophen-codeine in the treatment of acute pain in children with extremity injuries: a randomized clinical trial. Acad Emerg Med. 2009 Aug;16(8):711-6. — View Citation
Poonai N, Bhullar G, Lin K, Papini A, Mainprize D, Howard J, Teefy J, Bale M, Langford C, Lim R, Stitt L, Rieder MJ, Ali S. Oral administration of morphine versus ibuprofen to manage postfracture pain in children: a randomized trial. CMAJ. 2014 Dec 9;186( — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Visual analog scale | The pain is determined using a 100 mm scale. Patients are instructed to mark the level of pain they experience, with 0 mm indicating no pain and 100 mm indicating the presence of maximum pain. | 120 minute |
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