Pain, Central Sensitization, Kinesiophobia and Stress Level in Individuals With Temporomandibular Dysfunction

Pain Clinical Trial

Official title:

Investigation of the Relationship Between Pain, Central Sensitization, Kinesiophobia and Stress Level in Individuals With Temporomandibular Dysfunction

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05993494
• Other study ID #: KTU-FTR-2023/6
• Status: Recruiting
• Start date: May 15, 2023
• Est. completion date: July 30, 2024

Study information

• Verified date: March 2024
• Source: Karadeniz Technical University
• Contact: Nurhayat Korkmaz, PhDstudent
• Phone: +905387369062
• Email: krkmznrhyt[@]gmail.com
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

Temporomandibular dysfunction (TMD) is a musculoskeletal and neuromuscular system-related condition that affects the masticatory muscles, temporomandibular joint, and other related structures. Recent research has focused specifically on pain catastrophe, kinesiophobia, and central sensitization in individuals with TMD. Therefore, the aim of this study is to examine the relationship between pain, central sensitization, kinesiophobia and stress level in individuals with temporomandibular dysfunction.

Description:

Temporomandibular dysfunction (TMD) is a musculoskeletal and neuromuscular system-related condition that affects the masticatory muscles, temporomandibular joint, and other related structures. Psychological factors are stated as comorbid in individuals with TMD. Individuals with TMD-related pain show higher levels of stress, anxiety, depression, somatic awareness, pain catastrophizing, and kinesiophobia compared to controls. Therefore, recent research has focused on pain catastrophe, kinesiophobia, and central sensitization, especially in individuals with TMD. Therefore, the aim of this study is to examine the relationship between pain, central sensitization, kinesiophobia and stress level in individuals with temporomandibular dysfunction. Ninety patients aged 18-65 years, who have TME-related complaints for at least 3 months, and diagnosed with TMD as a result of clinical and radiological evaluation by a dentist will be included in the study.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 90
• Est. completion date: July 30, 2024
• Est. primary completion date: June 30, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Between the ages of 18-65,
• Having complaints related to TMJ for at least 3 months,
• Patients diagnosed with TMD as a result of clinical and radiological evaluation by the dentist

Exclusion Criteria:

• Cognitive problems,
• Any systemic joint or muscle disease (e.g. fibromyalgia, rheumatoid arthritis),
• Serious systemic diseases,
• Any neurological disorder (e.g. trigeminal neuralgia),
• Pregnancy, breastfeeding status,
• Previous treatment for TMJ or orofacial muscle pain

Related Conditions & MeSH terms

• Kinesiophobia
• Pain
• Temporomandibular Joint Disorders
• Temporomandibular Joint Dysfunction Syndrome

Locations

Country	Name	City	State
Turkey	Karadeniz Technical University	Trabzon

Sponsors (1)

Lead Sponsor	Collaborator
Karadeniz Technical University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Numeric Pain Scale	Pain Assessment	through study completion, an average of 1 year
Primary	Tampa Scale for Kinesiophobia	Kinesiophobia Assessment for temporomandibular joint dysfunction	through study completion, an average of 1 year
Primary	Perceived Stress Scale	Stress Assessment	through study completion, an average of 1 year
Primary	Central sensitization scale	Central sensitization Assessment	through study completion, an average of 1 year