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NCT05600023 Clinical Trial

The Effectiveness of Single Antibiotic Paste Nitrofurantoin Versus Double Antibiotic Paste

Pain Clinical Trial

Official title:
The Effectiveness of Single Antibiotic Paste Nitrofurantoin V/S Double Antibiotic Paste in Alleviation of Post-Operative Pain in Adult Patients Symptomatic Irreversible Pulpitis

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05600023
Other study ID # Intracanal medication
Secondary ID
Status Completed
Phase Phase 4
First received
Last updated
Start date August 1, 2022
Est. completion date October 24, 2022

Study information
Verified date October 2022
Source Altamash Institute of Dental Medicine
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

In our study, we used nitrofurantoin as a root canal medication in patients suffering from symptomatic irreversible pulpitis in alleviating pain compared with double antibiotic paste.

Description:

This study aims to compare the efficacy in alleviating pain between intracanal medicaments Nitrofurantoin versus double antibiotic paste.

Recruitment information / eligibility
Status Completed
Enrollment 60
Est. completion date October 24, 2022
Est. primary completion date October 24, 2022
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 50 Years
Eligibility Inclusion Criteria: - No medical history - no history of allergy to medications used in root canal treatment - patients suffering from Symptomatic Irreversible Pulpitis Exclusion Criteria: - Patients who were not suitable for conventional root canal treatment - multirooted teeth

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Nitrofurantoin
Nitrofurantoin has been found to successfully eradicate gram-negative bacteria such as Enterococcus faecalis that one of the most important bacteria in endodontic lesions
• Double Antibiotic
DAP is a combination of two antibiotics which are ciprofloxacin and metronidazole

Locations
Country Name City State
Pakistan Hira Danish Karachi Sindh

Sponsors (1)
Lead Sponsor Collaborator
Altamash Institute of Dental Medicine

Country where clinical trial is conducted

Pakistan, 

Outcome
Type Measure Description Time frame Safety issue
Primary To alleviate dental pain Dental pain will be measured by using Visual Analogue Scale(VAS) which is an 10-point scale from 0-10 where 0 represents no pain and 10 represents the worst pain measured 12 hours upto 72 hours following placement of intracanal medicament
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