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Clinical Trial Summary

Study aims to examine the effects of noninvasive brain stimulation on brain signals. This insight may have potential clinical implications for addiction, pain, and mental health populations. Participants will receive MRI and CT imaging. Participants receive low-intensity focused ultrasound (LIFU) to temporarily change brain activity. Participants then receive fMRI scans to measure changes in both resting and heat evoked brain signaling using a quantitative sensory testing device. Heart rate, blood pressure, respiratory rate, and skin moisture is monitored. Participants complete a battery of questionnaires, both behavioral and symptom monitoring. The study takes place over 4 study visits.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05303415
Study type Interventional
Source Virginia Polytechnic Institute and State University
Contact Jessica W Florig, MPH
Phone 540-526-2261
Email legonlab@vtc.vt.edu
Status Recruiting
Phase N/A
Start date May 6, 2022
Completion date May 2024

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