Pain Clinical Trial
Official title:
Benefit of the Association of Low Doses of Ketamine With Intravenous Morphine in the Treatment of Acute Severe Pain in Emergency Department
This study aims to determine the efficacy and safety of low dose ketamine in association
with IV morphine in the management of acute moderate to severe pain in emergency department.
The investigators hypothesize that low dose ketamine will result in more effective pain
control than morphine alone and will not be associated with an increase in adverse events.
Management of pain in the Emergency Department is challenging. Treatment of pain is most
often accomplished by parenteral opioids analgesics. However, the use of opioids alone for
pain control is often associated with inadequate analgesia and increased adverse events.
Low-dose ketamine has been shown to improve pain perception and produce an opioid-sparing
effect when given perioperatively.
Its use in the ED may probably play a role in maximizing analgesia.
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