Pain Clinical Trial
Official title:
PRL0706: Analgesic Use and Effectiveness
Opioid analgesics prescribed by dentists may contribute to the larger national issue of the use and abuse of the drug. On occasion dental pain may be sufficiently severe to support the use of opioids. This study used both dentist and patient input to evaluate the use of opioid and over-the-counter analgesics following one of seven coded common dental procedures. The study includes a five day patient follow up assessment of the effectiveness of the analgesic. Baseline questionnaires were completed by eligible participants, and they responded to the day 5 follow up questionnaires.
Specific Aims The overall objective of the proposed study is to determine (1) the pattern of
analgesic prescriptions (Rx and OTC) and recommendations (OTC) in dental practices; and (2)
the effectiveness of and side effects associated with these medications as measured by
patientreported outcomes (PROs).
Specific Aim 1: To document (a) dentists' postprocedural prescriptions and recommendations
for analgesic medication: and (b) the effectiveness of these medications and side effects
associated with their use as measured by PROs.
Specific Aim 2: To analyze by procedure class and anticipated pain severity the PROs of Rx
and OTC analgesic medications.
Specific Aim 3: Determine the incidence of analgesic side effects of Rx and OTC analgesic
medications.
The outcomes of Specific Aims 1-3 will be:
- The distribution of dentists' Rx/OTC prescriptions/recommendations by dentists for
anticipated pain severity.
- The effectiveness of different types of Rx and OTC analgesics (e.g., Rx NSAIDs vs. OTC
NSAIDs, Rx NSAIDs vs. Rx narcotics) by procedure class and anticipated pain severity.
- The incidence of analgesic side effects for Rx and OTC analgesics. Analysis of the
results and methods of the proposed research will furthermore serve as guidance in
designing a randomized PBRN clinical trial comparing the efficacy of and complications
associated with two or more analgesics.
;
Observational Model: Case-Only, Time Perspective: Prospective
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