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Characterization of the Analgesic Effect of CBD in Healthy, Normal Volunteers

Pain Clinical Trial

Official title:
Characterization of the Analgesic Effects of Oral CBD in Healthy, Normal Volunteers

Clinical Trial Summary

The purpose of this double-blind, placebo-controlled study is to determine the analgesic effects of cannabidiol (CBD), a chemical constituent found in cannabis that does not have intoxicating effects. The analgesic effects of CBD will be assessed using the Cold-Pressor Test (CPT), a laboratory model of pain which has predictive validity for the clinical use of analgesics.

Clinical Trial Description

This within-subject, double-blind, placebo-controlled study will assess the analgesic and subjective effects of a range of CBD doses (0, 200, 400, or 800 mg, po). Volunteers will participate in 4 outpatient laboratory sessions over the course of 4 weeks during which the analgesic effects of CBD will be assessed using the Cold-Pressor Test (CPT), a laboratory model of pain which has predictive validity for the clinical use of analgesics. The order of CBD dose will be randomized across participants. Secondary measures will include subjective and physiologic effects of CBD. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02751359
Study type Interventional
Source University of California, Los Angeles
Contact
Status Completed
Phase Phase 1/Phase 2
Start date July 2016
Completion date April 2020
View Details
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