Pain Clinical Trial
Official title:
The Effects of the Water-exchanged Colonoscopy on Adenoma Detection Rate: a Multicenter, Randomized, Single Blind, Control Trial
Water exchange method has been shown to reduce medication requirement and pain experienced
during colonoscopy. It may increase the adenoma detection rate (ADR). Water exchange provides
salvage cleansing and the refractive index of water (n equals about 1.3) is larger than that
of air, which creates optical distortion that likely contributes to objects appearing larger
underwater, making smaller lesions easier to visualize and it may help draw attention to
those smaller lesions during withdraw. These principles facilitate to the higher adenoma
detection rate.
There is a large number of literature on the adenoma detection rate during water exchange
colonoscopy, but most studies have been conducted in only one centre, simple-size, and under
sedation patients, the influence of adenoma detection rate under unsedation patients was
unclear.
The aim of this study is to compare the ADR of colonoscopy by using the water exchange method
versus the conventional air method in unsedation patients in multiple centers in China.
n/a
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