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NCT02087202 Clinical Trial

Hyperalgesia and NMDA Receptor Antagonist

Pain Clinical Trial

Official title:
Hyperalgesia and NMDA Receptor Antagonist

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT02087202
Other study ID # hyperalgesia
Secondary ID
Status Not yet recruiting
Phase N/A
First received March 12, 2014
Last updated March 12, 2014
Start date March 2014
Est. completion date July 2014

Study information
Verified date March 2014
Source Seoul National University Bundang Hospital
Contact n/a
Is FDA regulated No
Health authority Korea: Ministry of Food and Drug Safety
Study type Interventional

Clinical Trial Summary

NMDA receptor is administered and postoperative remote hyperalgesia is investigated.

Description:

NMDA receptor is adminstered and postoperative tertiary hyperalgesia is investigated.

QST and pain measures for remote hyperalgesia are compared between control and magnesium or ketamine group.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 90
Est. completion date July 2014
Est. primary completion date July 2014
Accepts healthy volunteers No
Gender Both
Age group 18 Years to 85 Years
Eligibility Inclusion Criteria:

- ASA1-2

Exclusion Criteria:

- contraindication to the study drugs

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Related Conditions & MeSH terms

Intervention

Drug:
• Magnesium Sulfate
magnesium sulfate is added to the patients
• ketamine
ketamine is added to the patients.

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Seoul National University Bundang Hospital

Outcome
Type Measure Description Time frame Safety issue
Primary pain pain (QST and pain measures )until 1 month from the end of the operation until 1 month from the end of the operation Yes
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