Risk Factors for Long-term Opioid Use

Pain Syndrome Clinical Trial

Official title:

Opioid Use Among Patients With Pain Syndromes Commonly Seeking Surgical Consultation

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04928131
• Other study ID #: 43803
• Status: Completed
• Start date: January 2007
• Est. completion date: February 2021

Study information

• Verified date: April 2022
• Source: Stanford University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Surgeons often see patients with pain to exclude organic pathology and consider surgical treatment. We examined factors associated with long-term opioid therapy among patients with foot/ankle, anorectal, and temporomandibular joint pain to aid clinical decision making.

Using the IBM MarketScan® Research Database, we conducted a retrospective cohort analysis of patients aged 18-64 with a clinical encounter for foot/ankle, anorectal, or temporomandibular joint pain (January 2007-September 2015). Multivariable logistic regression was used to estimate adjusted odds ratios for factors associated with long-term opioid therapy, including age, sex, geographic region, pain condition, psychiatric diagnoses, and surgical procedures in the previous year.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 1500392
• Est. completion date: February 2021
• Est. primary completion date: September 2015
• Gender: All
• Age group: 18 Years to 64 Years

Eligibility

Inclusion Criteria:

• 18-64 years old

• at least one encounter for anorectal, foot/ankle, or TMJ pain

• Marketscan continuous enrollment for 1 year prior and 1 year after the index pain encounter

Related Conditions & MeSH terms

• Pain Syndrome
• Syndrome

Intervention

Other:
• No intervention - retrospective observational cohort study

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Stanford University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Long-term opioid use	opioid prescriptions for 3 months.	>90 days of opioid supply
Secondary	new long-term opioid use	Opioid prescriptions for over 3 months in patients who have not had prior opioid prescriptions.	>90 days of opioid supply