Pregabalin and Analgesia After Laparoscopic Cholecystectomy

Pain Postoperative Clinical Trial

Official title: Preoperative Use of Pregabalin and Analgesia Levels After Laparoscopic Cholecystectomy

Status Completed

Clinical Trial Summary

The purpose of this study is to evaluate how effective is the preoperative administration of pregabalin 600mg, to attenuate postoperative pain and opioids consumption after laparoscopic cholecystectomy.

Clinical Trial Description

Acute pain frequently occurs during the postoperative period.Not treated acute postoperative pain may predict the development of chronic pain.Recently, the analgesic effect of pregabalin, as a part of a multimodal analgesia, has been evaluated in many studies. They have shown that pregabalin may have a role in the post operative pain management, as an adjunct. Pregabalin is an anticonvulsant and anxiolytic drug, which have a more favorable pharmacokinetic profile from its predecessor gabapentin.

Acute postoperative pain after laparoscopic cholecystectomy is complex in nature. Postoperative pain is the main complaint and the primary reason for delay discharge after laparoscopic cholecystectomy.The study includes patients undergoing laparoscopic cholecystectomy. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Supportive Care

Related Conditions & MeSH terms

• Pain Postoperative
• Pain, Postoperative

• NCT number: NCT01321801
• Study type: Interventional
• Source: Larissa University Hospital
• Status: Completed
• Phase: N/A
• Start date: November 2009
• Completion date: December 2010