Ultrasound-guided Deep and Superficial Serratus Anterior Plane Block

Pain Management Clinical Trial

Official title:

Comparison of Intraoperative Opioid Consumption, Emergence Time and Hemodynamic Stability Between Ultrasound-guided Deep and Superficial Serratus Anterior Plane Block During Video-assisted Thoracoscopic Lobectomy

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04252378
• Other study ID #: 2019-05-003-001
• Status: Recruiting
• Phase: N/A
• Start date: July 15, 2019
• Est. completion date: March 31, 2020

Study information

• Verified date: February 2020
• Source: Kyungpook National University Hospital
• Contact: Jimin Heo
• Phone: +82-53-420-5430
• Email: knuhmrc[@]knu.ac.kr
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study evaluates the difference of deep and superficial serratus anterior plane block on intraoperative opioid consumption, emergence time and hemodynamic stability in patients undergoing video-assisted thoracic surgery.

Description:

Thoracotomy is known as one of the most painful surgery. Thus, there is a development to reduce surgical stress in terms of operation technique, which is video-assisted thoracoscopic surgery. Although it has reduced postoperative pain and complications compared with thoracotomy, VATS is still quite painful operation. Serratus plane block is a novel technique which provide analgesic effect for lateral chest wall by blocking lateral branch of intercostal nerve. Two methods were proposed to target the top and bottom of the serratus anterior muscle. However, the difference of deep and superficial serratus anterior plane block during intraoperative period has not yet been studied.

In this study, therefore, the investigators decided to assess the difference of deep and superficial serratus anterior plane block on intraoperative opioid consumption, emergence time and hemodynamic stability in patients undergoing video-assisted thoracic surgery.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 56
• Est. completion date: March 31, 2020
• Est. primary completion date: February 29, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 75 Years

Eligibility

Inclusion Criteria:

• a) American Society of Anesthesiologists (ASA) physical status 1 or 2

• b) age 20-75 years

• c) elective three port Video-assisted thoracoscopic surgery (VATS) lobectomy.

Exclusion Criteria:

• a) a history of drug allergy for opioids or local anesthetics

• b) local infection at the injection site and systemic infection

• c) coagulopathy

• d) difficulty in understanding the study protocol

• e) refusal to participate

Related Conditions & MeSH terms

• Pain Management
• Thoracotomy

Intervention

Procedure:
• Deep Serratus Anterior Plane Block
Deep Serratus Anterior Plane Block was performed just before the start of surgery after anesthetic induction through ultrasound-guidance.
• Superficial Serratus Anterior Plane Block
Superficial Serratus Anterior Plane Block was performed just before the start of surgery after anesthetic induction through ultrasound-guidance.

Locations

Country	Name	City	State
Korea, Republic of	Kyungpook national university hospital	Daegu

Sponsors (1)

Lead Sponsor	Collaborator
Kyungpook National University Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Intraoperative remifentanil consumption	Intraoperative remifentanil consumption will be checked.	through study completion, an average of 1 year
Secondary	Emergence time	Emergence time is duration between the end of surgery and extubation. Emergence time will be checked.	through study completion, an average of 1 year
Secondary	Systolic blood pressure	Systolic blood pressure (mmHg) will be checked	through study completion, an average of 1 year
Secondary	Heart rate (HR) Heart rate	Heart rate (beats per minute) will be checked	through study completion, an average of 1 year
Secondary	Dose of rescue drugs used to control blood pressure and HR	Dose of rescue drugs used to control blood pressure and HR will be checked	through study completion, an average of 1 year
Secondary	Postoperative pain: numeric rating scale	Postoperative pain will be evaluated using a numeric rating scale (0 being no pain, 10 being worst pain imaginable)	30 minutes later operation