The Effects of Ultrasound-guided Serratus Plane Block During Video-assisted Thoracoscopic Lobectomy

Pain Management Clinical Trial

Official title:

The Effects of Ultrasound-guided Serratus Plane Block in Combination With General Anesthesia on Intraoperative Opioid Consumption, Emergence Time and Hemodynamic Stability During Video-assisted Thoracoscopic Lobectomy

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03718377
• Other study ID #: 2018-06-006-002
• Status: Recruiting
• Phase: N/A
• Start date: August 28, 2018
• Est. completion date: June 2019

Study information

• Verified date: February 2019
• Source: Kyungpook National University
• Contact: Jimin Heo
• Phone: 82-53-420-5430
• Email: knuhmrc[@]knu.ac.kr
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study evaluates the effects of serratus plane block on intraoperative opioid consumption, emergence time and hemodynamic stability in patients undergoing video-assisted thoracic surgery.

Description:

Thoracotomy is known as one of the most painful surgery. Thus, there is a development to reduce surgical stress in terms of operation technique, which is video-assisted thoracoscopic surgery. Although it has reduced postoperative pain and complications compared with thoracotomy, VATS is still quite painful operation.

Serratus plane block is a novel technique which provide analgesic effect for lateral chest wall by blocking lateral branch of intercostal nerve. It has been reported to be used for pain management including rib fracture, herpes zoster, and postoperative pain. It has become a popular analgesic modality because it is easy to perform and relatively safe. However, the effect of serratus plane block during intraoperative period has not yet been studied.

In this study, therefore, the investigators decided to assess the effect of serratus plane block on intraoperative opioid consumption, emergence time and hemodynamic stability in patients undergoing video-assisted thoracic surgery.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 50
• Est. completion date: June 2019
• Est. primary completion date: June 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 75 Years

Eligibility

Inclusion Criteria:

• American Society of Anesthesiologists physical status classification I-III for three port video-assisted thoracic surgery lobectomy under general anesthesia

Exclusion Criteria:

• History of allergic reaction to local anesthetics, coagulopathy, local infection at the injection site, and systemic infection.

Related Conditions & MeSH terms

• Anesthesia, Conduction
• Pain Management

Intervention

Procedure:
• Serratus plane block
The subjects were received serratus plane block in the regional-anesthesia unit out of operation room before induction of general anesthesia. And, video-assisted thoracic surgery was performed under balanced general anesthesia.
• General anesthesia only
Video-assisted thoracic surgery was performed under balanced general anesthesia without serratus plane block

Locations

Country	Name	City	State
Korea, Republic of	Kyungpook national university hospital	Daegu

Sponsors (1)

Lead Sponsor	Collaborator
Kyungpook National University

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Intraoperative remifentanil consumption	Intraoperative remifentanil consumption will be checked.	through study completion, an average of 1 year
Secondary	Emergence time	Emergence time is duration between the end of surgery and extubation. Emergence time will be checked.	through study completion, an average of 1 year
Secondary	Systolic blood pressure	Systolic blood pressure (mmHg) will be checked	through study completion, an average of 1 year
Secondary	Heart rate	Heart rate (beats per minute) will be checked	through study completion, an average of 1 year
Secondary	Dose of rescue drugs used to control blood pressure and HR	Dose of rescue drugs used to control blood pressure and HR will be checked	through study completion, an average of 1 year