The Effects of Three Oral Medications on Post-operative Pain Following Endodontic Treatment

Pain Management Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01178203
• Other study ID #: IAU-1083
• Status: Completed
• Phase: Phase 1/Phase 2
• First received: August 9, 2010
• Last updated: August 9, 2010
• Start date: July 2010
• Est. completion date: August 2010

Study information

• Verified date: July 2010
• Source: Azad University of Medical Sciences
• Contact: n/a
• Is FDA regulated: No
• Health authority: Iran: Ministry of Health
• Study type: Interventional

Clinical Trial Summary

Aim: eliminating or reducing pain following endodontic treatment is of great importance. The aim of this study is to compare the effects of Tramadol, Novafen and Naproxen on post-operative pain following instrumentation of root canals in teeth with irreversible pulpitis. Sample size: one hundred patients considering the inclusion and exclusion criteria were selected. Intervention and outcome: The effect of Tramadol, Novafen and Naproxen on post-operative pain following instrumentation of root canals in teeth with irreversible pulpitis was evaluated.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 0
• Est. completion date: August 2010
• Est. primary completion date: July 2010
• Gender: Both
• Age group: 20 Years to 60 Years

Eligibility

Inclusion Criteria:

1. The subjects were 20-60 years of age with no systemic diseases and females were not pregnant;

2. No history of taking any analgesics or other drugs prior to presenting for treatment;

3. Patients had moderate to severe pain associated with irreversible pulpitis in single-rooted premolars or anterior teeth.

Exclusion Criteria:

Study Design

Intervention Model: Parallel Assignment, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Pain Management
• Pulpitis

Intervention

Drug:
• Placebo
Placebo
• Tramadol
Tab, 100mg in 6, 12 and 24 hours after root canal treatment
• Novafen
325 mg in 6, 12 and 24 hours after root canal treatment
• Naproxen
Tab, 500 mg in 6, 12, and 24 hours after root canal treatment

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Azad University of Medical Sciences