Pain, Chronic Clinical Trial
Official title:
Paracetamol Discontinuation in the Elderly After Long-term Consumption
To investigate if long-term treatment of paracetamol can be discontinued without no worsening on pain, health-related quality-of-life and level of function compared to continuing paracetamol treatment in patients aged 65 years or more.
Aim: To investigate if long-term treatment of paracetamol can be discontinued without
worsening on pain, health-related quality-of-life and level of function compared to
continuing paracetamol treatment in patients aged 65 years or more.
Trial design: Patients are randomized to either arm 1: standard care (paracetamol
continuation) or arm 2: experimental treatment (placebo).
The investigation is double-blinded.
Patients are screened and recruited from Department of respiratory medicine at Copenhagen
University Hospital Bispebjerg. Patients with a daily consumption of 3 grams or more of
prescribed paracetamol and who comply with the other eligibility criteria will be invited to
participate in the trial and asked for written, informed consent. If given we collect data
regarding the patient's medications, any medication changes during the intervention and
followup, frailty (FRAIL Scale), self-reported history of falls, recent admissions,
self-reported health-related quality of life (EQ-5D-5L), level of function tested by hand
grib strength and sitting-rising test, and death.
Data is collected at baseline and after 2 weeks when ending treatment intervention, and a 26
week follow-up.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05452499 -
Pain Neuroscience Education and Therapeutic Exercise as a Treatment for Breast Cancer Survivors Living With Sequelae
|
N/A | |
| Recruiting |
NCT05037682 -
Pain and Opioid Management in Older Adults
|
N/A | |
| Completed |
NCT04080037 -
Assessing Opioid Care Practices Using CPV Patient Simulation Modules
|
N/A | |
| Recruiting |
NCT05382962 -
iCanCope With Post-Operative Pain (iCanCope PostOp)
|
N/A | |
| Recruiting |
NCT04285112 -
SPRINT: Signature for Pain Recovery IN Teens
|
||
| Active, not recruiting |
NCT04850079 -
EHR Precision Drug Treatment in Neonates
|
||
| Completed |
NCT03271151 -
Effect of Duloxetine on Opioid Use After Total Knee Arthroplasty
|
Phase 4 | |
| Completed |
NCT03272139 -
Interscalene Block Versus Superior Trunk Block
|
Phase 4 | |
| Completed |
NCT03886142 -
Platelet Rich Plasma Versus Radio Frequency for Chronic Knee Arthritis
|
N/A | |
| Recruiting |
NCT05761392 -
APP-based Precise Management System of Chronic Intractable Pain
|
N/A | |
| Recruiting |
NCT05877157 -
Pain AND Opioids After Surgery
|
||
| Completed |
NCT03947749 -
Linking Epigenomics With Prescription Opioid Abuse and High Impact Musculoskeletal Pain
|
||
| Completed |
NCT03280017 -
Ketamine With Multilevel Paravertebral Block for Post Video-assisted Thoracic Surgery Pain
|
Phase 4 | |
| Recruiting |
NCT04874038 -
Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN)
|
Phase 3 | |
| Completed |
NCT04280796 -
Changes in Affective Pain Processing in Human Volunteers
|
N/A | |
| Withdrawn |
NCT05125978 -
Efficacy and Safety of Canadá Association in the Treatment of Chronic Pain
|
Phase 2 | |
| Not yet recruiting |
NCT04328805 -
Pain Reduction and Changes in Upper Limb Function Produced by an Ibuprofen Treatment in Carpal Tunnel Syndrome.
|
Phase 4 | |
| Completed |
NCT04976738 -
A Study of Cybis™ 10:25 THC:CBD Oil in Adults With Chronic Back/Neck Pain
|
Phase 1/Phase 2 | |
| Completed |
NCT04089618 -
Meditation Based Lifestyle Modification in Chronic Pain
|
N/A | |
| Recruiting |
NCT05699837 -
Alpha Entrainment for Pain and Sleep (Extension)
|
N/A |