Dependence on Analgesics in Chronic Non-cancer Pain

Pain, Chronic Clinical Trial

— DISCORDANCE  

Official title:

Dependence on Analgesics in Chronic Non-cancer Pain: Comparison of the Perceptions of the Algologist Physician and the Perception of the Patient.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03346408
• Other study ID #: RC31/17/0094
• Secondary ID: 2017-A01826-47
• Status: Completed
• Start date: November 4, 2017
• Est. completion date: December 18, 2018

Study information

• Verified date: May 2024
• Source: University Hospital, Toulouse
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The identification of an addiction to opioid analgesics has become strong recommendation for the purpose of improving the clinical management of the patients. However, the success of the patient's clinical management, in terms of analgesia and treatment of drug dependence, rests on the acceptance of this management by the patient himself. The main objective of this study is to evaluate the factors associated to the discrepancy between the assessment of dependence on analgesic drugs by the algologist and the perception that the patient with non-cancer chronic pain has of this dependence.

Description:

The long-term use of opioid analgesics for the treatment of chronic non-cancer pain exposes patients to the risk of developing drug dependence on these psychoactive drugs with loss of control of their use. In general medicine as well as in algology consultation, the identification of an addiction to opioid analgesics (and even misuse as a gateway to addiction) have thus become strong recommendations for the purpose of improving the management of the patients. However, the success of the patient's clinical management, in terms of analgesia and treatment of drug dependence, rests on the acceptance of this management by the patient himself.

The discrepancy between the assessment of drug dependence on analgesic drugs by the algologist and the perception that the patient has of this dependence will be investigated through a multicentre cross-sectional descriptive survey performed in pain treatment centres in France.

In addition to opioid analgesics, other pharmacological classes used for analgesic use will be investigated as they are concerned with the development of drug dependence. This is particularly the case for gabapentins.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 220
• Est. completion date: December 18, 2018
• Est. primary completion date: November 19, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• suffering from chronic non-cancer pain,

• taking at least one analgesic medication

Exclusion Criteria:

• Patient minor or major protected by the law (under tutelage),

• Patient with chronic pain of cancerous origin,

• Opposition of the patient to be included in the study,

• Patient not having the overall skills to complete a self-questionnaire: major difficulties in understanding the French language and / or reading / writing difficulties.

Related Conditions & MeSH terms

• Chronic Pain
• Pain, Chronic

Intervention

Behavioral:
• Questionnaire
patient (self-questionnaire) and algologist physician (questionnaire)

Locations

Country	Name	City	State
France	University Hospital Bordeaux	Bordeaux
France	University Hospital Clermont-Ferrand	Clermont-Ferrand
France	University Hospital Limoges	Limoges
France	University Hospital Marseille	Marseille
France	University Hospital Montpellier	Montpellier
France	University Hospital Nice	Nice
France	University HospitalToulouse	Toulouse

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Toulouse

Country where clinical trial is conducted

France, 

References & Publications (1)

Roussin A, Cisse Z, Rousseau V, Roche G, Lestrade C, Cauchie A, Delage N, Donnet A, Van Obberghen E, Wood C, Lapeyre-Mestre M, Cantagrel N. Discordance between pain specialists and patients on the perception of dependence on pain medication: A multi-centr — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	discrepancy between the assessment of dependence on analgesic drugs by the algologist and the perception of the patient	The patients will complete a self-questionnaire and the algologist physician will fill another questionnaire.	Baseline
Secondary	Consumption drugs	Patient questionnaire for associated drug	Baseline
Secondary	Anxiety	Hospital Anxiety and Depression Scale (HAD Scale)	Baseline