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Pain, Chronic clinical trials

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NCT ID: NCT05659134 Active, not recruiting - Pain, Chronic Clinical Trials

Comparison of Alfredson and Silbernagel Protocol in Competitive Athletes With Achilles Tendinopathy

Start date: December 2, 2022
Phase: N/A
Study type: Interventional

A 6-week randomized clinical trial (RCT) with a 46-week follow-up compared the effect of Alfredson and Silbernagel eccentric programs for the treatment of AT. The primary outcome was a change in the Victorian Institute of Sport Assessment - Achilles (VISA-A) scale from baseline to 12 months. The study was approved by the Ethics Committee of the Faculty of Physical Education and Sport, Charles University (Project number: 254/2021). All participants provided written informed consent before participation.

NCT ID: NCT05636345 Completed - Pain, Chronic Clinical Trials

An Evaluation of a Public Health Campaign in a High School Setting Targeting Pain Related Knowledge and Beliefs

Start date: March 17, 2022
Phase: N/A
Study type: Interventional

The beliefs held by students lead to behaviours in response to their pain which can be both helpful or a hindrance to how they manage their pain. The one-day education event aims to educate the cohort on the contemporary scientific understanding of persistent pain. It is hoped this event will result in an improvement in the alignment of beliefs and behaviours to contemporary understanding of persistent pain. The principal aim is to evaluate the pre-post beliefs about pain following a one-day pain education event.

NCT ID: NCT05628246 Recruiting - Pain, Chronic Clinical Trials

Telemedicine Improves Pain-related Disabilities in Following up Cancer Pain Outpatient

Start date: January 19, 2023
Phase: N/A
Study type: Interventional

Cancer is the second leading cause of death worldwide, with approximately 18.1 million new cases and 9.6 million deaths reported in 2018. Cancer-related pain is experienced by 50-70% of patients, with a higher prevalence at advanced disease stages (66.4%). Since the development of WHO's cancer pain guidelines, several studies have reported good relief of symptoms and suffering for a majority of patients. Recent reports suggest that up to 50% of patients still report insufficient pain control. Patients with cancer often present with multiple symptoms and functional decline. Evidence supports multidisciplinary approaches to address symptoms and suffering, including early palliative care referral From review literatures we found that the telemedicine group had significantly higher quality of life than the usual care group. In addition, the telemedicine group had lower anxiety and depression scores than the usual care group. Therefore, we will conduct the non-randomized controlled study of using telemedicine comparing to conventional in-person at OPD in hospitalized cancer pain patients. The purpose of this study is to assess the pain interference by using the Brief Pain Inventory (BPI) and to compare between the in-person group and the telemedicine group. To assess the cost-effectiveness of telemedicine for reducing symptoms associated with cancer and its treatment.

NCT ID: NCT05627830 Recruiting - Pain, Chronic Clinical Trials

Ultrasound Guided Versus Non-Guided Prolotherapy for Internal Derangement of Temporomandibular Joint.

Start date: November 10, 2022
Phase: N/A
Study type: Interventional

Ultrasound Guided Versus Non-Guided Prolotherapy for Treatment of Internal Derangement of Temporomandibular joint. Rationale for conducting the research: The most critical cause for guided prolotherapy is to specify the accurate location of glenoid fossa and the disc space while prolotherapy procedure, and to adjust the needle insertion to according to articular eminence, mandibular condyle, and intra-articular space as anatomical variations. The vibration of ultrasound waves generates a heat so there is a thermal effective for prolotherapy effusion in the TMJ space.

NCT ID: NCT05619510 Recruiting - Depression Clinical Trials

Pain Reduction Through Empowered Recovery (PRIME) Study

PRIME
Start date: March 31, 2023
Phase: N/A
Study type: Interventional

Chronic pain and depression or low mood are often experience by women who age with or into disabilities. Due to various factors women with disabilities often experience this cycle of pain and depression. Both of these conditions can be debilitating and lead to declines in health. Treating these conditions simultaneously, particularly , in older adults can be complicated due to side effects, risks of poor access to pain management and mental health care , and complications from other co occuring conditions. In order to address this cycle in older women with disabilities the investigators are testing the Women in Pain Reduction through Improved Mood and Empowerment (PRIME) study. The PRIME intervention includes four in person visits by a nurse to the women's homes where the participants set goals regarding pain and depression and the nurse helps the participants strategize ways to meet these goals. The second component of the study will be eight group sessions virtually with other participants in the study. The group sessions will be led by a clinical psychologist who will engage in Acceptance Commitment Therapy with the women.

NCT ID: NCT05617027 Not yet recruiting - Pain, Chronic Clinical Trials

Relieving Chronic Pain in Older Adults With Transcranial Direct Current Stimulation

tDCS-pain
Start date: December 1, 2023
Phase: N/A
Study type: Interventional

The primary objective of this study is to determine, in a healthcare setting, the effectiveness of actual tDCS in reducing pain compared with placebo tDCS. This is a multicenter randomized controlled trial with parallel groups (real tDCS vs. placebo) blinded to participants, assessors and tDCS providers. The real tDCS group will receive a daily 20-minute session of tDCS (current intensity = 2 mA), for 5 consecutive days, while the placebo tDCS group will receive an equivalent treatment, but the current will be stopped after the first 30 seconds. The study will take place in 5 rehabilitation clinics in 3 Quebec regions. One hundred and fifty (150) seniors aged 65 years or older with chronic (> 6 months), moderate to severe musculoskeletal pain will be recruited (50 participants/region). Follow-ups will take place at 1 week and 3 months post-treatment. The primary dependent variable is pain intensity (numerical scale from 0 to 10). Secondary variables will be measured using standardized and validated questionnaires: 1) pain-related interferences (physical function, mood, quality of life) and 2) perception of post-TDCS changes. Neurophysiological measures (pain control pathways).

NCT ID: NCT05616702 Recruiting - Low Back Pain Clinical Trials

Effectiveness of Pressure Biofeedback Therapy and Progressive Muscle Relaxation Technique in Improving Pain and Disability Among Patients With Non-Specific Low Back Pain

Start date: October 15, 2022
Phase: N/A
Study type: Interventional

Low back pain is common MSK disease with prevalence of 60 to 70 percent. Patients with low back discomfort are typically treated conservatively by physical therapists. Progressive muscles relaxation technique has been shown in several studies to reduce chronic back pain and increase flexibility. pressure biofeedback therapy works on Intra abdominal pressure.it helps to alleviate compression on lumbar spine and support the adjacent lumbar spine.The aim of this randomized controlled trial is to determine the effectiveness of pressure biofeedback training (Pr.BFB) in combination with progressive muscles relaxation technique (PMR) & progressive muscles relaxation training alone on pain, disability, ROM & endurance of muscles among nonspecific chronic low back pain patients.

NCT ID: NCT05612750 Recruiting - Pain, Chronic Clinical Trials

Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRESS Study

PROGRESS
Start date: January 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to conduct a pragmatic clinical trial comparing the effectiveness of: (1) 8-week cognitive behavioral therapy for chronic pain (pain-CBT; sixteen hours total treatment time); and (2) a 1-session pain relief skills intervention for chronic pain (Empowered Relief; two hours total treatment time).

NCT ID: NCT05612165 Recruiting - Pain, Chronic Clinical Trials

Effectiveness and Safety of tDCS for Pain

Start date: June 9, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to verify the effectiveness and safty of transcranial direct current stimulation in patients with central post-stroke pain.

NCT ID: NCT05608733 Not yet recruiting - Pain, Chronic Clinical Trials

Continuous Sciatic Nerve Block vs Epidural Analgesia in Lower Limb Amputation for Postoperative Pain

Ampupain
Start date: December 2022
Phase: Phase 3
Study type: Interventional

Controlled clinical trial of two parallel groups, with random assignment 1:1, non-inferiority, blinded for the patient, for who administers the intervention and for who analyzes the data. 112 participants