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Pain, Cancer clinical trials

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NCT ID: NCT06240390 Not yet recruiting - Pain Cancer Clinical Trials

Effectiveness of Percutaneous Neuromodulation vs Pharmacological Treatment in Cancer Patients With Anterior Knee Pain

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

the goal of this clinical trial is to compare in cancer patients: Is ultrasound-guided percutaneous neuromodulation useful for Anterior Knee Pain relief in cancer patients? Participants will receive treatments of ultrasound-guided percutaneous neuromodulation and pharmacological treatment Researchers will compare ultrasound-guided percutaneous neuromodulation versus pharmacological treatment to see if Anterior Knee Pain is reduced

NCT ID: NCT06240377 Not yet recruiting - Pain Cancer Clinical Trials

Effectiveness of NMP and TDCS vs Pharmacological Treatment in Cancer Patients With Lower Limb Pain

Start date: June 1, 2024
Phase: N/A
Study type: Interventional

the goal of this clinical trial is to compare in cancer patients: Is ultrasound-guided percutaneous neuromodulation useful for lower limb pain relief in cancer patients? Is direct current transcranial stimulation useful for relieving lower limb pain in cancer patients? Participants will recive treatments of ultrasound-guided percutaneous neuromodulation and DC Transcranial Stimulation Researchers will compare ultrasound-guided percutaneous neuromodulation and DC Transcranial Stimulation to see if pain in the lower extremities is reduced

NCT ID: NCT06160323 Recruiting - Clinical trials for Pancreatic Cancer Non-resectable

Upfront EUS CGN/CPN vs Conventional Step up Approach for Inoperable Painful Pancreatic Cancer

Start date: November 10, 2023
Phase: N/A
Study type: Interventional

Patients with unresectable pancreatic cancer are often demoralized by intractable, persistent and incapacitating pain. It must be managed aggressively and strong opioids are recommended as the mainstay of treatment. However, patients develop opioid-related adverse effects. EUS-guided celiac plexus neurolysis (CPN) and celiac ganglion neurolysis (CGN) has been shown to provide high efficacy for pain control. The optimal timing, however, is in debate.

NCT ID: NCT06101849 Recruiting - Breast Cancer Clinical Trials

Chronic Cancer Pain Management Program

ICMP
Start date: January 3, 2024
Phase: N/A
Study type: Interventional

The goal of this research study is to evaluate an online inter-professional pain management program for survivors of breast cancer. The main questions it aims to answer: 1. whether this treatment will help address the pain management concerns of patients, 2. whether it is feasible to offer this treatment in the future as multi-centre randomized controlled trial (RCT). Participants will be asked to attend a 6-week online pain management group sessions (1h/week). Participants will also be asked to fill out questionnaires before and after the program completion.

NCT ID: NCT05450419 Recruiting - Advanced Cancer Clinical Trials

The Role of Vitamin D3 Supplementation in Advanced Cancer Patients With Pain

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

Many patients with cancer have insufficient vitamin D levels, and low vitamin D levels are associated with increased 'all-cause mortality' and especially mortality due to cancer. Vitamin D has anti-cancer effects, including anti-proliferation, anti-angiogenesis, and anti-inflammation. Besides, low vitamin D levels are associated with higher opioid dose usage, fatigue, and impaired quality of life in palliative cancer patients. Therefore, patients with low vitamin D levels needs instant vitamin D supplement with "stoss therapy" which is single high dose vitamin D with maintenance dose by enteral route. The stoss therapy has been applied in many fields, including neonatal, diabetes, hemodialysis, heart failure, osteoporosis. In critically ill patients, such as surgical, medical, burn intensive unit admission patients, high dose vitamin D supplement was associated lower mortality amount the vitamin D deficiency patients. This study aims for evaluating the effects of enteral high dose vitamin D supplement on advanced cancer patients with pain, serum concentration changes of vitamin D, quality of life, symptom burden, and analyze its correlation with inflammation, immune and nutritional markers.

NCT ID: NCT05299047 Recruiting - Pain Cancer Clinical Trials

Fluoroscopic Anterior Approach Versus Ultrasound Guided Superior Hypogastric Plexus Neurolysis in Cancer Pelvic Pain

Start date: January 1, 2022
Phase: Phase 2
Study type: Interventional

Cancer related pelvic pain can be debilitating and difficult to treat. Superior hypogastric plexus neurolysis (SHPN) is considered to be an option for adequately relieving pain, with fewer side effects and improving the quality of life

NCT ID: NCT05236647 Recruiting - Pain Cancer Clinical Trials

Subcutaneous Versus Intravenous Morphine When Switching From Oral to Parenteral Route in Palliative Cancer Patients

SIM
Start date: March 8, 2022
Phase: Phase 3
Study type: Interventional

The investigators aim to establish whether the intravenous or the subcutaneous route of administration has clinically significant advantages when parenteral administration of morphine is started with a combination of continuous infusion and bolus doses in palliative cancer patients. Patients admitted to a Hospital palliative medicine unit with an indication for parenteral administration of morphine will be recruited. The patients will have two similar infusion pumps with continuous infusion and bolus function. One infusion pump will be connected to an intravenous line, the other to a subcutaneous line. One pump contains morphine, one placebo. The primary endpoint is the time from initiation of infusion with titration to the final infusion rate that provides pain control is reached.

NCT ID: NCT05067257 Suspended - Pain Clinical Trials

Study to Assess Epidural Resiniferatoxin for the Treatment of Intractable Pain Associated With Advanced Cancer

Start date: September 2025
Phase: Phase 2
Study type: Interventional

This Phase 2 study assesses the safety and efficacy of a single injection of Resiniferatoxin versus placebo for the treatment of intractable advanced cancer pain.

NCT ID: NCT04872556 Terminated - Joint Pain Clinical Trials

Evaluation of the Effect of Laser Acupuncture on Taxane Acute Pain Syndrome Patients

Start date: May 13, 2021
Phase: N/A
Study type: Interventional

This is a prospectively randomized and double-blinded clinical study. Cancer patients were suffered from the taxanes-induced joint pain, and would be advised to receive laser acupuncture in specific points to relieve pain. Clinical effects of analgesic changes would be evaluated before and after the intervention. The inflammation associated indices would be further analyzed to reveal the therapeutic mechanism of laser acupuncture. The laser acupuncture was expected to relief taxanes-induced adverse effects in patients and also can improve patients' life quality.

NCT ID: NCT04782206 Not yet recruiting - Pain, Chronic Clinical Trials

S3 Root Pulsed Radiofrequency Added to Superior Hypogstric Plexus Block

Start date: March 15, 2021
Phase: N/A
Study type: Interventional

The investigators hypothesis that adding pulsed radiofrequency neuromodulation at S3 nerve root to superior hypogastric plexus chemical neurolysis improves analgesia in patients with chronic pelvic cancer pain.