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Pain, Acute clinical trials

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NCT ID: NCT05545033 Completed - Pain, Acute Clinical Trials

Use of Virtual Reality in Pain Management in Hospitalized Patients

Start date: January 20, 2021
Phase: N/A
Study type: Interventional

Acute and chronic non-cancer pain is a common healthcare problem locally and globally, leading to many inpatient admissions for poorly controlled pain. The World Health Organisation has declared that access to adequate pain control is a fundamental human right. Yet in our current practice, both acute and chronic non-cancer pain remain poorly controlled. There is passive over-reliance on pharmacological agents and interventional procedures in the management of pain. The opioid epidemic with issues of dependence, misuse, and overdose is especially concerning. Therefore, there is a pertinent clinical need to find sustainable non-pharmacological adjuncts in the complex management of pain. Virtual reality (VR) involves the use of technology to create a three-dimensional multisensory artificial environment replacing real-world sensory inputs. Initially created solely for entertainment purposes, VR applications have since expanded and made its way into healthcare. In Pain Medicine, the application of VR has been promising. There is currently no VR study done in our local population who suffer from pain issues. In our study, we aim to test the feasibility of applying the use of VR in patients admitted inpatient due to pain issues. We believe that VR can be used as an adjunctive tool improve pain management and patient satisfaction.

NCT ID: NCT05524337 Recruiting - Pain, Acute Clinical Trials

White Noise and Therapeutic Touch on Pain and Comfort Level in Newborns During Heel Lance

noisetouch
Start date: July 1, 2022
Phase: N/A
Study type: Interventional

This randomized controlled study was planned to evaluate the effects of listening to white noise and therapeutic touch on physiological parameters, pain and comfort level during the heel blood collection procedure on infants who gave birth at 32 weeks and above and were given to their mothers in Atatürk Training and Research Hospital.

NCT ID: NCT05518877 Recruiting - Pain, Acute Clinical Trials

Low Dose Ketamine Infusion for Analgesia in the Emergency Department to Reduce Side Effects

Start date: December 7, 2022
Phase: Phase 4
Study type: Interventional

This will be an intent to treat prospective, double blind, double-dummy, randomized trial. Our primary objective is the reduction of side effects of sub dissociative dose ketamine given by slow intravenous (IV) infusion over 30 minutes vs. 15 minutes in the treatment of acute, severe pain in Emergency Department (ED) patients. The secondary objective will be to maintain adequate pain control (as defined by a Visual Analog Scale (VAS) score of ≤ 5cm) at 30 minutes for both groups.

NCT ID: NCT05510271 Completed - Pain, Acute Clinical Trials

Pain in Newborn Heel Blood Collection

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

This study was conducted to evaluate the effect of white noise and therapeutic touch on pain in newborn heel blood collection.Questions including the sex of the newborns, postnatal age, gestational age, birth weight, height, head and chest circumference, feeding style, nutritional status in the last half hour, and previous heel blood collection were collected with the "Information Form".The Newborn Infant Pain Scale (NIPS) was used to evaluate the pain levels of newborns.

NCT ID: NCT05509075 Recruiting - Pain, Acute Clinical Trials

Nutraceuticals and Functional Foods

Start date: November 12, 2019
Phase:
Study type: Observational

Supplements and functional foods are now readily available and usable by the general population. Many supplemnets are commonly used in poly-treated patients where interactions or adverse events may develop, therefore we evaluate in the rela life the use of nutraceuticals, their clinical effects and the development of adverse drug reactions

NCT ID: NCT05498025 Completed - Pain, Acute Clinical Trials

The Effect of a Charcoal Deactivation Pouch on Opioid Disposal After Cesarean Delivery

Start date: February 21, 2023
Phase: N/A
Study type: Interventional

Background: There is scarce literature investigating how patients dispose of unused opioid supplies after their cesarean postoperative pain has faded. The Office of the Surgeon General has identified research on the prevention of opioid use disorder area as well as research on the management of pain as a "Surgeon General Priority" that needs urgent investigation. Hypothesis: At least 33% of postpartum women discharged home with an opioid prescription and a drug deactivation pouch will use the pouch to dispose of remaining opioids within 30 days of delivery. Methods: This is a prospective single arm interventional pilot study.

NCT ID: NCT05482919 Completed - Pain Clinical Trials

The Adolescent Surgery Experience: A Mixed Methods Analysis

Start date: June 14, 2022
Phase:
Study type: Observational

New chronic pain and opioid use are reported as prevalent among adolescents undergoing major surgery; many unanswered questions remain regarding recovery and the anticipated pain trajectory across procedures and the interaction between pain treatment, acute inflammation and new chronic pain. Broadly, the proposed study will characterize the adolescent's postoperative recovery experience, and establish the anticipated pain trajectory across a range of procedures.

NCT ID: NCT05476575 Recruiting - Pain, Acute Clinical Trials

The Effect of Perioperative Hydrogen Inhalation on Post-operative Pain and Inflammation Cytokines

Start date: October 28, 2021
Phase: N/A
Study type: Interventional

To understand the impact of perioperative hydrogen inhalation on post-operative pain control and serum inflammation markers

NCT ID: NCT05471557 Not yet recruiting - Aging Clinical Trials

Effects of Acute Pain on Motor Learning in Young vs Older Adults

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

To date, the effects of pain on motor learning have not been thoroughly investigated, particularly in older adults. Broadly, the purpose of this research is to investigate the impact of acute pain on locomotor learning and its retention in older adults. The investigators hypothesize that acute pain impairs retention of locomotor learning in young and older adults and that in older adults, these deficits are worsened and are related to the degree of normal age-related cognitive decline.

NCT ID: NCT05468684 Not yet recruiting - Neck Pain Clinical Trials

PROCO Neck: The Course and Neuroplasticity in Neck Pain-Associated Disorders and Whiplash-Associated Disorders

Start date: September 1, 2022
Phase:
Study type: Observational [Patient Registry]

Neck pain-associated disorders (NAD) and whiplash-associated disorders (WAD) are major health problems. NAD has a lifetime prevalence of 54%. Although the majority of patients recovers within the first three months, a minority develops persistent pain. WAD, in contrast, is reported less frequently, but patients are often suffering more badly. Patients with chronic symptoms represent a considerable burden in terms of pain, suffering, health care needs, and social costs. Findings on the natural course of NAD and WAD reflect the necessity to identify factors besides pain related to the persistence of symptoms. First, alterations of input and processing of multiple sensory modalities causing movement control impairment can result in persistent symptoms and affect the quality of life. Besides, findings of psychosocial factors predictive of pain outcomes support the growing body of research proposing a bidirectional relationship between somatic and psychosocial variables. In particular, there is a pressing need to investigate pain-related activity patterns, besides fear-avoidance behavior in NAD and WAD. Maladaptive activity pattern have an impact on on pain and disability in the long-term prognosis. Mt important, given the high prevalence of NAD and WAD, the cortical representation of the cervical spine has not yet been investigated and, reports on neuroplasticity remain scarce. These shortcomings should be addressed to provide evidence for the temporal aspect of neuroplasticity and its involvement in pain persistence. Hypotheses: We hypothesize I. that impaired sensorimotor abilities, mental health at baseline increase pain intensity and disability during measurement. II. that maladaptive pain-related activity patterns avoidance and overactivity at baseline are prognostic factors for pain persistence and disability. III. that the WAD cohort shows more depression, anxiety and stress compared to the NAD cohort.