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Pacemaker Ddd clinical trials

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NCT ID: NCT06377046 Not yet recruiting - Atrial Fibrillation Clinical Trials

Accelerated Pacing in Patients Undergoing Pace-and-ablate Strategy With LBBAP: a Randomized Controlled Pilot Trial

PACE-AF
Start date: May 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to determine the effect of accelerated pacing (pacemaker lower rate programmed to 80bpm) compared to pacing at the standard programmed lower rate of 60bpm in symptomatic atrial fibrillation patients undergoing pace-and-ablate strategy with LBBAP. The main question it aims to answer is: - To determine the effect of accelerated pacing on health-related quality of life compared to the current standard of care. Secondary questions it aims to answer are: - To study the acute hemodynamic effect of different (accelerated) pacing rates on pulmonary capillary wedge pressure, cardiac output and arterial blood pressure among atrial fibrillation patients undergoing pace-and-ablate strategy. - To study the long-term effects (at 6 months) of accelerated pacing compared to the current standard of care among atrial fibrillation patients undergoing pace-and-ablate strategy on: - NT pro BNP levels - device detected atrial fibrillation burden and daily activity - echocardiographic measurements (LVEF, left ventricular ejection fraction; LVEDD, left ventricular end- diastolic diameter; LVESD, left ventricular end-systolic diameter; LAVI left atrial volume index; diastolic parameters; strain

NCT ID: NCT06371846 Recruiting - Pacemaker DDD Clinical Trials

Comparative Study of the Surface Electrocardiogram Signals During the Implantation of Conduction System Pacing Devices

Start date: March 14, 2023
Phase:
Study type: Observational [Patient Registry]

Introduction and objectives: Left bundle branch area pacing (LBBAP), is a novel modality of physiologic pacing that requires an adequate assessment of the endocardium as well as the body-surface electrocardiographic signals for a successful pacing-lead implantation. The objective of the study consist of assessing if LBBAP criteria, specifically septal and left bundle branch pacing (LBBP) criteria, can be satisfactory measured using the signals resulting from different cardiac pacing analyzers (PSAs) by comparing them to the 'conventional' signals obtained from multichannel polygraph systems (MPSs) during the implantation procedure. Methods: Comparative observational, prospective, multicenter study between the signals obtained by PSA vs MPS of consecutive patients who underwent a LBBAP strategy as first intention.

NCT ID: NCT06318130 Recruiting - Pacemaker DDD Clinical Trials

Comparison of Pacing Lead Design on Left Bundle Branch Pacing Outcomes

LEAD-LBP
Start date: January 1, 2023
Phase: N/A
Study type: Interventional

This trial seeks to evaluate the performance of the extendable helix, stylet-driven pacing lead (EHL) compared to the fixed helix, lumenless pacing lead (FHL) during left bundle branch pacing (LBBP), with respect to enduring left bundle branch capture on follow-up, incidence of acute lead failure, pacing characteristics including QRS duration, pacing thresholds, R-wave amplitudes and lead impedance, and finally, safety profile during LBBP implantation. These data will guide future lead selection during LBBP implantation in achieving improved procedural success and optimal lead performance.

NCT ID: NCT06094114 Completed - Bradycardia Clinical Trials

Evaluation of VDD Leadless Pacing System During Exercise

Start date: April 1, 2022
Phase:
Study type: Observational

The study is a non-randomized, active prospective observational study permitting to report the behavior of Micra AV pacemaker during an exercise. Only patients who were previously implanted with a Micra MC1AVR01 can be enrolled in the study. Exercise test is part of the standard clinical care practice for this patients population during the first year follow-up.

NCT ID: NCT06068699 Completed - Adherence, Patient Clinical Trials

Postcards to Improve Remote Monitoring Adherence Among Veterans

Start date: May 1, 2020
Phase: N/A
Study type: Interventional

We tested the effect of informational postcards on improving remote monitoring adherence among Veterans with pacemakers and implantable cardioverter-defibrillators in a stepped-wedge randomized controlled trial.

NCT ID: NCT06045143 Not yet recruiting - Pacemaker DDD Clinical Trials

Right Ventricular Septal Versus Apical Pacing: Echocardiographic Study

Start date: October 1, 2023
Phase:
Study type: Observational

This study aims to compare the effect right ventricular apical versus septal pacing on left ventricular function by deformation imaging using 2D speckle tracking echocardiography.

NCT ID: NCT05884359 Recruiting - Clinical trials for Left Bundle-Branch Block

Left Bundle Branch Area Mapping for Conduction System Pacing

Start date: June 1, 2023
Phase:
Study type: Observational

This study will utilize 3D mapping as a tool to explore electro-anatomical and electrocardiographic characteristics of the Left Bundle Branch Area. We plan on prospectively reviewing the data found from 3D mapping the left bundle branch implantation cases and using the data to improve understanding of electro-anatomical characteristics of this area for a better definition of the implantation target and depth.

NCT ID: NCT05883514 Recruiting - Pacemaker DDD Clinical Trials

The Feasibility of Motivational Interviewing on Emotional Intelligence, Dispositional Optimism, and Adherence to Care Practices Among Patients With Permanent Pacemaker

Start date: April 15, 2023
Phase: N/A
Study type: Interventional

A cardiac pacemaker is an artificial apparatus that stimulates the myocardium electrically to depolarize, to begin a contraction when the heart's natural pacemaker does not work properly. Pacemakers are essential when dysrhythmias or conduction defects compromise the electrical system and the heart's hemodynamic response. The current status aimed to assess the feasibility of motivational interviewing on emotional intelligence, dispositional optimism, and adherence to care practices among patients with permanent pacemaker.

NCT ID: NCT05868616 Recruiting - Heart Failure Clinical Trials

Non-Invasive Method for Evaluation of Cardiac Resynchronization Therapy

NIME-CRT
Start date: March 21, 2023
Phase:
Study type: Observational

Left bundle branch block (LBBB) exists in about 25% of patients with congestive heart failure and is associated with worsened prognosis. Cardiac resynchronization therapy (CRT) has been one of the most important advancements in the past two decades for patients with LBBB heart failure. However, 30-40% of patients receiving a CRT do not benefit from it. In this study, the investigators will test a noninvasive device to evaluate acute effect of CRT during implantation and at follow-up CRT controls. In addition, echocardiography will be performed during CRT turned ON and OFF to visualize the changes in intraventricular flow and functional parameters of the heart.

NCT ID: NCT05695534 Not yet recruiting - Pacemaker DDD Clinical Trials

Use of VR in Patients' Education Prior to Implantation of PPM

Start date: January 25, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to compare standard education with VR augmented education in patients prior to implantation of a permanent pacemaker.