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Oxidative Stress clinical trials

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NCT ID: NCT04310748 Completed - Anesthesia Clinical Trials

Effects of TIVA and Inhalation Anesthesia on Oxidative Stress Factors During Hypotensive Anesthesia

Start date: May 1, 2020
Phase: N/A
Study type: Interventional

Total intravenous anesthesia (TIVA) and inhalation anesthesia are two anesthesia methods that can be preferred for the maintenance of anesthesia. Sevoflurane and propofol are drugs used frequently in these methods. This study aims to investigate and compare the effects of inhalation anesthesia using sevoflurane and TIVA using propofol on oxidative stress in patients undergoing controlled hypotensive anesthesia.

NCT ID: NCT04298996 Completed - Dental Caries Clinical Trials

Effect of Passive Smoking on Oxidative Stress and Dental Caries in Children

Start date: November 16, 2016
Phase:
Study type: Observational

The purpose of the present study was to determine the effect of passive smoking on oxidative stress and dental caries in children.A total of 180 children were included to the study as follows; 90 children exposed to passive smoking, and 90 children in the control group (unexposed controls). Also demographic data were recorded (age, gender, parental education levels, child's tooth-brushing habit and child's daily dietary sugar exposure, family income). Dental examination of children were performed and caries prevalence of the patients were recorded. Unstimulated saliva samples were collected from children. Saliva 'cotinine levels' and oxidative stress markers 'total antioxidant status' (TAS), and' total oxidant status' (TOS) were evaluated by using Enzyme-linked immunosorbent assay (ELISA). The obtained data parameters of the two groups were evaluated and comparison was performed.

NCT ID: NCT04292548 Completed - Dental Caries Clinical Trials

Salivary TAS, TOS, LL-37 and Dental Status in Passive Smoking Children

Start date: November 16, 2016
Phase:
Study type: Observational

The aim of the present study was to determine the effect of passive smoking on the levels of salivary TAS, TOS, LL-37 and dental status in children.In the study the parents of children were asked to fill out a complete survey about smoking habits. After filling out the questionnaire, according to the survey results, a total of 180 children were included to the study as follows; 90 children exposed to passive smoking, and 90 children in the control group (unexposed controls). Also demographic data were recorded (age, gender, parental education levels, child's tooth-brushing habit and child's daily dietary sugar exposure, family income). Dental examination of children were performed and caries prevalance of the patients were recorded. Unstimulated saliva samples were collected from children. Saliva 'cotinine levels' which are expected to increase in passive smoking group; 'antimicrobial peptide LL-37' and oxidative stress markers 'total antioxidant status' (TAS), and' total oxidant status' (TOS) were evaluated by using Enzyme-linked immunosorbent assay (ELISA). The obtained data parameters of the two groups were evaluated and comparison was performed.

NCT ID: NCT04292314 Completed - Oxidative Stress Clinical Trials

Hydroxy Urea, Omega 3, Nigella Sativa,Honey on Oxidative Stress and Iron Chelation in Pediatric Major Thalassemia

Start date: November 1, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of the present study is evaluating the strength of combination therapy of hydroxy urea, omega 3, nigella sativa and honey on antioxidant-oxidant status (OXIDATIVE STRESS) in response to reactive oxygen species production (LIPID PEROXIDATION) and their effect on iron intoxication (IRON CHELATION) in pediatric major thalassemia.

NCT ID: NCT04258553 Completed - Oxidative Stress Clinical Trials

Thiol Disulfide Balance in Cervix Cancer

Start date: September 1, 2018
Phase:
Study type: Observational

The aim of this research is to evaluate thiol‑disulfide balance in cervix cancer patients

NCT ID: NCT04252105 Completed - Oxidative Stress Clinical Trials

Antioxidant-rich Diet and Oxidative Stress in Healthy Preschoolers

Start date: August 28, 2019
Phase: N/A
Study type: Interventional

Uncontrolled and prolonged oxidative stress plays an important role in the onset and progression of cardiovascular disease, hyperlipidemia, diabetes, and various cancers. Given that many diseases can start as early as childhood, eating patterns in childhood and preventing oxidative damage can have beneficial long-term health effects. Antioxidant-rich foods can slow down the progression of chronic diseases. In Slovenian kindergartens (and schools) children consume up to 70% of their daily energy and nutritional needs, so what is offered to them is very important. This study will evaluate the hypothesis that providing an antioxidant-rich diet in kindergartens can result in the reduction of biomarkers of oxidative stress.

NCT ID: NCT04212819 Completed - Anemia Clinical Trials

Before and After Erythrocyte Suspension Transfusion

Start date: January 1, 2014
Phase: N/A
Study type: Interventional

Hypoperfusion, hypoxia and ischemia occurs in circulation as a result of anemia. All of these situations lead to oxidative stress and endothelial dysfunction in the organism. In this study, the investigators aimed to investigate the oxidant-antioxidant balance and asymmetric dimethylarginine (ADMA) levels in patients that have symptomatic anemia in need of erythrocyte suspension (ES) transfusion. To the best of the investigators knowledge, there have been few studies in the literature on anemia and total oxidant, total antioxidant and ADMA levels. We aimed to observe changes in oxidative - antioxidant ADMA levels before and after ES transfusion.

NCT ID: NCT04177641 Completed - Oxidative Stress Clinical Trials

Evaluation of Thioldisulfide Balance in Cervical Preinvasive Lesions

Start date: September 20, 2018
Phase:
Study type: Observational

The purpose of this study is to investigate Thiol-disulfide balance in patients with cervical preinvasive lesions

NCT ID: NCT04175873 Completed - Anesthesia Clinical Trials

The Effect of Music Therapy on Glutathione Peroxidase, Malondialdehyde and Pain in Oocyt Pick Up Patients.

Start date: November 25, 2019
Phase: N/A
Study type: Interventional

It is used by music therapists to help the social, physical, emotional, psychological and psychological needs of patients. In a study, music has a positive effect on pain, anxiety, depression, shortness of breath, mood, facial expression and speech . The aim of this study was to investigate analgesia consumption during egg collection and postoperative period of music therapy and to compare and evaluate oxidative stress parameters in blood and follicle fluids.

NCT ID: NCT04175067 Completed - Oxidative Stress Clinical Trials

Evaluation of Thiol Disulfide Balance in Stage 1 Endometrium Cancer

Start date: August 1, 2018
Phase:
Study type: Observational

The purpose of this study is to investigate thiol‑disulfide balance in early stage endometrium cancer patients.