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ENDOCUR - Modulation of Endotoxaemia Via Curcumin Intake in Healthy Overweight Adults — ENDOCUR  

Overweight Clinical Trial

Official title:
Modulation of Endotoxaemia Via Curcumin Intake in Healthy Overweight Adults

Clinical Trial Summary

Chronic diseases such as diabetes, cardiovascular diseases and cancer are a major burden on the Scottish population. Obesity and inflammation have strong links to these diseases. One of the mechanisms explaining the relationship between low-grade inflammation and excess weight is "endotoxaemia". We wish to study this phenomenon, when small components coming from our gut bacteria can pass into the bloodstream, raising the body's defences. Diet can modulate endotoxaemia. In this study, we propose to use curcumin, in a capsule form, to modulate endotoxaemia. Curcumin comes from turmeric, which is widely used as a spice. In this study, we want to test the effect of consuming curcumin extract to the composition of the gut microbiota, post-meal endotoxaemia, and inflammatory markers in blood.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03329781
Study type Interventional
Source University of Glasgow
Contact
Status Completed
Phase N/A
Start date February 2015
Completion date January 2018
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