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NCT01218945 Clinical Trial

Development of Bone Grafts Using Adipose Derived Stem Cells and Different Scaffolds

Overweight Clinical Trial

Official title:
Development of Bone Grafts Using Adipose Derived Stem Cells and Different Scaffolds: Impact of Pre-engineered Capillaries in Critical Size Grafts

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01218945
Other study ID # Bone-ZH09
Secondary ID
Status Completed
Phase N/A
First received September 29, 2010
Last updated June 18, 2013
Start date November 2009
Est. completion date December 2012

Study information
Verified date June 2013
Source University of Zurich
Contact n/a
Is FDA regulated No
Health authority Switzerland: Swissmedic
Study type Observational

Clinical Trial Summary

The repair of large osseous defects remains still unsolved. Aim of this study is to isolate and cultivate fat-derived progenitor cells and differentiation into osteoblasts. Therefore, our research idea is to pre-engineer large synthetic bone grafts and study the vascularization process in vivo.

Recruitment information / eligibility
Status Completed
Enrollment 33
Est. completion date December 2012
Est. primary completion date December 2012
Accepts healthy volunteers No
Gender Both
Age group 18 Years to 70 Years
Eligibility Inclusion criteria:

- German-speaking patients aged 18-70 admitted to the Clinic of Reconstructive surgery for reconstructive surgery and fat-excision.

Exclusion criteria:

- Drug-abuse, neoplasia and metabolic disorders

Study Design

Time Perspective: Prospective

Related Conditions & MeSH terms

Intervention

Procedure:
• Cell Culture
Aim of this study is to isolate and cultivate fat-derived progenitor cells and differentiation into osteoblasts. Therefore, our research idea is to pre-engineer large synthetic bone grafts and study the vascularization process in vivo.

Locations
Country Name City State
Switzerland University Hospital Zurich, Clinic of Reconstructive Surgery Zurich ZH

Sponsors (1)
Lead Sponsor Collaborator
University of Zurich

Country where clinical trial is conducted

Switzerland, 

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