WS®1442 in Slightly Overweight Subjects

Status Completed

Clinical Trial Summary

The purpose of this study is to test:

1. Safety of 900 mg or 1800 mg of WS® 1442 per day in overweight subjects (BMI 25 to 29,9 kg/m²)

2. Pharmacodynamic effect of WS® 1442 on endothelial function versus nordic walking training in overweight subjects

Clinical Trial Description

60 overweight subjects with a BMI of 25 to 29,9 kg/m2 are to be included. The safety of 900 mg/1800 mg per day WS® 1442 is determined by adverse events, laboratory parameters, vital signs as well as by a treadmill test at the beginning and the end of the study. Endothelial function measured before and after two different training modalities is compared to that measured before and after intake of two different doses of WS® 1442. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator)

Related Conditions & MeSH terms

Overweight

Clinical Trial Details

NCT number	NCT00982501
Study type	Interventional
Source	Dr. Willmar Schwabe GmbH & Co. KG
Contact
Status	Completed
Phase	Phase 1
Start date	June 2008
Completion date	February 2011

View Details

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