Clinical Trials Logo
  1. Home
  2. Overweight or Obesity
  3. NCT04207879

Modified Atkins Diet for Overweight and Obesity

Overweight or Obesity Clinical Trial

Official title:
Longitudinal Profiling of Gut Microbiome in Overweight or Obese Participants on a Modified Atkins Diet: a Prospective Cohort Study

Clinical Trial Summary

The aim of the study is to investigate dynamic changes in biochemical metabolism, gut microbiome and its metabolites among overweight and obese participants while they are on a modified Atkins Diets.

Clinical Trial Description

The mechanisms of obesity are complex, involved in genes, environment, life style, and systemic and adipose tissue inflammation. Dysbiosis of gut microbiome is considered to make a difference in obesity. On the other hand, both long-term and short-term dietary interventions can induce changes in the body composition and structure and function of gut microbiome. However, it is not really clear how gut microbiome changes along with weight loss in overweight or obese. In the present study, investigators aim to characterize the gut microbiome among overweight or obese participants on a modified Atkins diets. The stool and blood samples were collected by an interval of every 5% and 10% of weight loss, respectively. Data collecting mainly covers: 1) body composition analysis ; 2) obesity related biochemical metabolism; 3) measurement of gut microbiome using metagenome and 16S rRNA sequencing techniques; 4) metabolomics of serum and gut microbiome; 5) measurement of physical activity and diets using questionnaires. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04207879
Study type Observational
Source Hebei Medical University Third Hospital
Contact
Status Active, not recruiting
Phase
Start date January 1, 2020
Completion date December 2023
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT06013163 - A Phase 1 Study to Evaluate EMP22 PD and EMP16 PK Versus Xenical® in Healthy Volunteers Phase 1
Active, not recruiting NCT03843424 - Treatment Efforts Addressing Child Weight Management by Unifying Patients, Parents & Providers N/A
Not yet recruiting NCT06360536 - Remotely Delivered Resistance Training for Cardiometabolic Health Among Black Women N/A
Not yet recruiting NCT05997576 - A Study of TG103 Injection in Non-diabetic Overweight or Obesity Phase 3
Recruiting NCT04763291 - Cardiovascular and InflammAging Study N/A
Active, not recruiting NCT04399460 - The Effects of Long-term Consumption of Full-fat Dairy Products on Satiety, Body Weight and Glycemic Control N/A
Completed NCT04451824 - Examination of Circumferential Reduction N/A
Completed NCT04110717 - Electrical Vestibular Nerve Stimulation (VeNS) Compared to Sham Control as a Means of Reducing Excess Body Weight N/A
Completed NCT05561855 - T2DM Intensity Lifestyle Intervention N/A
Active, not recruiting NCT04100200 - Berries, Inflammation, and Gut Microbiome N/A
Recruiting NCT06125964 - eMOTION Formative Study N/A
Recruiting NCT06087822 - Multicenter Trial Investigating Performance and Safety of the Medical Device SiPore21® N/A
Active, not recruiting NCT04328233 - Impact of Time-Restricted Eating on Metabolic Homeostasis, Inflammation and Oxidative Stress in Metabolic Syndrome N/A
Completed NCT06091761 - Thread Embedding Acupuncture Combined With Auricular Acupuncture for Overweight and Obesity N/A
Completed NCT04894344 - Education to Decrease in Sodium Intake Evaluated With 24 Hour Urinary Sodium Excretion (RCT) N/A
Completed NCT05713461 - Physical Exercise in Obesity for Health and Quality of Life. N/A
Not yet recruiting NCT06054698 - Efficacy and Safety of HRS9531 Injections in Overweight or Obese Subjects Phase 2
Not yet recruiting NCT02823912 - Capsaicin Effect on Cytokines Profile in Dyslipidemia Phase 2/Phase 3
Completed NCT05104151 - Efficacy of a Nutritive Bar, in Reduction of Weight, Body Fat and Control of Appetite N/A
Completed NCT04786925 - Precision Nutrition Strategies for Improving the Quality of Life of Pre-senior and Senior Populations N/A