Time-restricted Eating in Morning Chronotype

Status Recruiting

Clinical Trial Summary

Overweight and obesity are highly prevalent conditions worldwide, despite active research of new interventions over decades. Current interventions include medications or bariatric surgery, but these approaches cannot be used in all patients and require clear indications and a close multidisciplinary management. Therefore most patients and physicians rely on lifestyle interventions, focusing on a balanced diet and physical exercise. Recent studies have uncovered that energy metabolism is also regulated by circadian rhythms, which depend on spontaneous diurnal oscillations of the central clock, retinal sensing of ambient light, and daily feeding-fasting cycles. The chronotype has an influence on behavioral patterns, where some people describe that they are more alert in the morning or in the evening: The morning or evening chronotypes, respectively. However, in modern societies, many people are exposed to external cues in misalignment with their circadians clocks. The mismatch between the individual chronotype and the social/work life can lead to metabolic disorders. Time-restricted eating (TRE), i.e. energy intake limited to certain windows of time without restricting calories, is an appealing approach because it proposes to realign the circadian clocks with external cues provided by the timing of food intake, thus leading to better metabolic outcomes. The investigators speculate that the TRE intervention needs to be personalized to reach efficacy in a broader population. To tailor the TRE intervention to each individual and harmonize their eating patterns in accordance to their chronotype, the investigators plan to test early TRE vs. late TRE vs. active control in overweight and obese individuals with morning chronotype.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04618133
Study type	Interventional
Source	University Hospital, Geneva
Contact	Tinh-Hai Collet, MD
Phone	+41-22-372.93.49
Email	tinh-hai.collet@hcuge.ch
Status	Recruiting
Phase	N/A
Start date	January 4, 2021
Completion date	June 30, 2023

View Details

See also
Status	Clinical Trial	Phase
Not yet recruiting	`NCT03994419` - PErioperAtive CHildhood ObesitY
Recruiting	`NCT05354245` - Using a Complex Carbohydrate Mixture to Steer Fermentation and Improve Metabolism in Adults With Overweight and Prediabetes (DISTAL)	N/A
Completed	`NCT03602001` - Attentive Eating for Weight Loss	N/A
Recruiting	`NCT06269159` - The Power of 24-hour: Co-designing Intervention Components
Completed	`NCT03377244` - Healthy Body Healthy Souls in the Marshallese Population	N/A
Completed	`NCT02996864` - Location-based Smartphone Technology to Guide College Students Healthy Choices Ph II	N/A
Completed	`NCT04647149` - Effects of Early and Delayed Time-restricted Eating in Adults With Overweight and Obesity	N/A
Terminated	`NCT03914066` - A Group-based Treatment of Overweight and Obesity in Primary Care	N/A
Completed	`NCT03685656` - Effect of ANACA3 Slimming Gel on Loss of Abdominal and Thigh Circumferences in Healthy Volunteers	N/A
Completed	`NCT05051579` - A Study of LY3502970 in Participants With Obesity or Overweight With Weight-related Comorbidities	Phase 2
Completed	`NCT04611477` - Effect of Synbiotic 365 on Body Composition in Overweight and Obese Individuals	N/A
Active, not recruiting	`NCT05330247` - Cut Down on Carbohydrate in the Dietary Therapy of Type 2 Diabetes - The Meal Box Study	N/A
Completed	`NCT03599115` - Effects of Inhibitory Control Training in Eating Behaviors	N/A
Recruiting	`NCT05938894` - Train Your Brain - Executive Function	N/A
Recruiting	`NCT06094231` - Treating Patients With Renal Impairment and Altered Glucose MetAbolism With TherapeutIc Carbohydrate Restriction and Sglt2-Inhibiton - a Pilot Study	N/A
Recruiting	`NCT05987306` - A Self-compassion Focused Intervention for Internalized Weight Bias and Weight Loss	N/A
Completed	`NCT03792685` - Looking for Personalized Nutrition for Obesity/Type 2 Diabetes Mellitus Prevention	N/A
Completed	`NCT05055362` - Effect a Honey, Spice-blended Baked Good Has on Salivary Inflammation Markers in Adults: a Pilot Study	N/A
Completed	`NCT04520256` - Rapid Evaluation of Innovative Intervention Components to Maximize the Health Benefits of Behavioral Obesity Treatment Delivered Online: An Application of Multiphase Optimization Strategy	Phase 2/Phase 3
Completed	`NCT04979234` - A Single Centre, Prospective Feasibility Study to Evaluate the Efficacy of an Endoluminal-suturing Device (Endomina) on Severe Obstructive Sleep Apnea Syndrome	N/A