Gender Specific Responses of Overweight and Obese Adults to Sprint Interval Training

Overweight and Obesity Clinical Trial

Official title:

Gender Specific Responses of Overweight and Obese Adults to Sprint Interval Training on Anthropometric Variables

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04155827
• Other study ID #: UMFB1001
• Status: Completed
• Phase: N/A
• Start date: February 4, 2020
• Est. completion date: November 23, 2020

Study information

• Verified date: November 2020
• Source: Universiti Tunku Abdul Rahman
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Overweight and Obesity is a growing health problem worldwide. Lifestyle changes such as decreased physical activity, increased sedentary behaviour and unhealthy eating habits has contribute to this problem. According to World Health Organization (2016), more than 1.9 billion adults aged 18 years and older were overweight (39% of men and 40% of women).Regular exercise is the key contributor to energy expenditure and is essential for energy balance and weight control. Interval training (IT) has been commonly used for decades with purpose to improve body health and reduce weight loss and this exercise differs from the conventional aerobic exercise and endurance exercise as IT typically involves repeated bouts of relatively intense exercise interspersed by periods of lower- intensity effort or complete rest for recovery. One of the most common type of IT is sprint interval training (SIT). SIT involves 'supramaximal' effort (>100% VO2max) work bouts, traditionally structured as four to six 30s all-out effort and each round separated by 4 minutes of recovery period of a low intensity exercise. Potential physiological adaptation of SIT are highlighted by various studies reporting cardiovascular, skeletal muscle adaptations, increase fat oxidation that facilitate increases in both aerobic and anaerobic performance. In addition, SIT is able to improve maximal rate of oxygen consumption (VO2max), at the same time improving the peripheral vascular structure and function, enzymes of fat metabolism and increases insulin sensitivity. Previous SIT studies have included young healthy men and women, healthy obese young women, all of which have shown that SIT is effective for fat loss and improvement of some health parameters. However, whether SIT protocol is equally effective in improving the anthropometric measures in men and women remain unknown.

Description:

Total of 80 eligible male (n=40) and female (n=40) young adults will be equally recruited using block randomization and chosen based on the inclusion and exclusion criteria. Before the study, all participants will be informed of the potential risks and benefits of the study. During the study period, participants will be instructed to avoid any form of physical activity besides the study protocol. Both groups will perform SIT protocol on a electromagnetically braked cycle ergometer three times per week for 6 weeks. Every session, participants start with a 5 minutes warm up at 50- 60% of heart rate maximum (HRmax) and follow by four 30-s all out bouts intersperse with 4 minutes of recovery (passive or no load cycling). For confirmation of all-out effort, participant are required to maintain his or her cycling cadence at least 60 rpm or above. Intervention will end with a 5 minutes cool down at 50- 60% of HRmax. Total duration for each session will be 28 minutes. If a participant misses fewer than three sessions per week non- consecutively, the sessions missed will be replace at the end of period. However, if participants misses three or more sessions, he or she will be excluded from the study. Outcome measures will be assessed at baseline and at end of 6 weeks of intervention.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 35
• Est. completion date: November 23, 2020
• Est. primary completion date: November 16, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 25 Years

Eligibility

Inclusion Criteria:

• BMI?23kg/m2(WHO for Asia-Pacific region)

• No history of metabolic, hormonal, orthopedic, or cardiovascular diseases

• No current use of prescribed medication including oral contraception

Exclusion Criteria:

• Contraindications to physical activity assessed by Physical Activity Readiness Questionnaire-PAR-Q

• Undergoes any surgical or hormone treatment

Related Conditions & MeSH terms

• Overweight
• Overweight and Obesity

Intervention

Other:
• SIT
Sprint interval training of 4*4, with 30 seconds of all out workout followed by 4 minutes of active recovery for 4 cycles.

Locations

Country	Name	City	State
Malaysia	Universiti Tunku Abdul Rahman	Kajang	Selangor

Sponsors (1)

Lead Sponsor	Collaborator
Universiti Tunku Abdul Rahman

Country where clinical trial is conducted

Malaysia, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	BMI for change		At baseline (before intervention begin) and post training (end of 6 weeks).
Primary	Waist Circumference for change		At baseline (before intervention begin) and post training (end of 6 weeks).
Primary	Total Fat % for change		At baseline (before intervention begin) and post training (end of 6 weeks).
Primary	Lean Muscle Mass for change		At baseline (before intervention begin) and post training (end of 6 weeks).
Primary	skin Fold Measurement for change		At baseline (before intervention begin) and post training (end of 6 weeks).