Effects of Ketogenic Diet in Divers Breathing Enriched Air Nitrox

Status Completed

Clinical Trial Summary

Overweight divers face a challenging activity such as immersions, starting from a higher levels of circulating cytokines and oxidative stress. Ketogenic Diet (KD) is described as effective in weight loss, in countering inflammation and oxidative stress, and used in the control of drug-refractory seizures.

The aim of our pilot study was to evaluate if a ketosis state induced by a specific dietary regime, may have a protective effect on oxidative stress damages and inflammatory status, that accompanies both overweight and diving activities.

Blood and urine samples from six overweight divers were obtained a) before (CTRL) and after a dive breathing Enriched Air Nitrox and performing light underwater exercise (NTRX), b) after a dive (same conditions) performed after 7 days of KD (K-NTRX). We measured urinary 8-isoprostane and 8-OH-2-deoxyguanosine evaluating lipids peroxidation and DNA oxidative damages. Plasmatic IL-1beta, IL-6 and TNF-alpha levels were measured to investigate the inflammatory status.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03114176
Study type	Interventional
Source	University of Padova
Contact
Status	Completed
Phase	N/A
Start date	May 25, 2016
Completion date	July 10, 2016

View Details

See also
Status	Clinical Trial	Phase
Not yet recruiting	`NCT03994419` - PErioperAtive CHildhood ObesitY
Recruiting	`NCT05354245` - Using a Complex Carbohydrate Mixture to Steer Fermentation and Improve Metabolism in Adults With Overweight and Prediabetes (DISTAL)	N/A
Completed	`NCT03602001` - Attentive Eating for Weight Loss	N/A
Recruiting	`NCT06269159` - The Power of 24-hour: Co-designing Intervention Components
Completed	`NCT03377244` - Healthy Body Healthy Souls in the Marshallese Population	N/A
Completed	`NCT02996864` - Location-based Smartphone Technology to Guide College Students Healthy Choices Ph II	N/A
Terminated	`NCT03914066` - A Group-based Treatment of Overweight and Obesity in Primary Care	N/A
Completed	`NCT04647149` - Effects of Early and Delayed Time-restricted Eating in Adults With Overweight and Obesity	N/A
Completed	`NCT03685656` - Effect of ANACA3 Slimming Gel on Loss of Abdominal and Thigh Circumferences in Healthy Volunteers	N/A
Completed	`NCT05051579` - A Study of LY3502970 in Participants With Obesity or Overweight With Weight-related Comorbidities	Phase 2
Completed	`NCT04611477` - Effect of Synbiotic 365 on Body Composition in Overweight and Obese Individuals	N/A
Active, not recruiting	`NCT05330247` - Cut Down on Carbohydrate in the Dietary Therapy of Type 2 Diabetes - The Meal Box Study	N/A
Completed	`NCT03599115` - Effects of Inhibitory Control Training in Eating Behaviors	N/A
Recruiting	`NCT06094231` - Treating Patients With Renal Impairment and Altered Glucose MetAbolism With TherapeutIc Carbohydrate Restriction and Sglt2-Inhibiton - a Pilot Study	N/A
Recruiting	`NCT05938894` - Train Your Brain - Executive Function	N/A
Recruiting	`NCT05987306` - A Self-compassion Focused Intervention for Internalized Weight Bias and Weight Loss	N/A
Completed	`NCT03792685` - Looking for Personalized Nutrition for Obesity/Type 2 Diabetes Mellitus Prevention	N/A
Completed	`NCT05055362` - Effect a Honey, Spice-blended Baked Good Has on Salivary Inflammation Markers in Adults: a Pilot Study	N/A
Completed	`NCT04520256` - Rapid Evaluation of Innovative Intervention Components to Maximize the Health Benefits of Behavioral Obesity Treatment Delivered Online: An Application of Multiphase Optimization Strategy	Phase 2/Phase 3
Completed	`NCT04979234` - A Single Centre, Prospective Feasibility Study to Evaluate the Efficacy of an Endoluminal-suturing Device (Endomina) on Severe Obstructive Sleep Apnea Syndrome	N/A