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Clinical Trial Summary

This study aims to evaluate the safety and effectiveness of zimberelimab combined with metformin in treating relapsed/persistent ovarian clear cell carcinoma.


Clinical Trial Description

Ovarian clear cell carcinoma (OCCC) is one of the rare subtypes of ovarian cancer, yet its prognosis is extremely poor. Previous studies indicate that PD-1 inhibitors may have clinical benefits for OCCC patients. This single-arm, single-center, pilot study evaluates the safety and effectiveness of zimberelimab combined with metformin in treating relapsed/persistent ovarian clear cell carcinoma. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05759312
Study type Interventional
Source Fudan University
Contact Libing Xiang
Phone 862164041990
Email xiang.libing@zs-hospital.sh.cn
Status Not yet recruiting
Phase Phase 1/Phase 2
Start date March 2023
Completion date February 2025

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