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NCT00419627 Clinical Trial

Proteomic Analysis of HLA Complex in Solid Cancers: Breast, Ovary, Colon, Rectum, Stomach, and Pancreas

Ovarian Cancer Clinical Trial

Official title:
Proteomic Analysis of Serology and Peptides Presented on the HLA Complex of Breast, Ovarian, Colon, Rectal, Gastric and Pancreatic Adenocarcinoma.

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT00419627
Other study ID # ProtHYMC
Secondary ID
Status Not yet recruiting
Phase N/A
First received January 5, 2007
Last updated January 5, 2007
Start date February 2007

Study information
Verified date January 2007
Source Hillel Yaffe Medical Center
Contact Itamar Ashkenazi, M.D.
Phone 972-4-6304761
Email i_ashkenazi@yahoo.com
Is FDA regulated No
Health authority Israel: Ethics Commission
Study type Observational

Clinical Trial Summary

The purpose of this study is to evaluate the presence of proteins in solid tumors which may lead to an immune response

Description:

The main objective of the study is to evaluate which proteins are presented by the HLA complex of solid tumors. Secondary objectives include to evaluate whether an immune response specific to these proteins has actually been provoked and whether there is a similar immune response following recurrence. Real specimens will be evaluated using PCR and mass spectrometry.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 160
Est. completion date
Est. primary completion date
Accepts healthy volunteers
Gender Both
Age group N/A and older
Eligibility Inclusion Criteria:

- Patients with adenocarcinoma of breast, colon, rectum, ovary , stomach, pancreas

Exclusion Criteria:

- Withdrawal of consent

- Small specimen which does not allow to retrieve tissue without interfering with pathologic evaluation

Study Design

Observational Model: Natural History, Time Perspective: Longitudinal

Related Conditions & MeSH terms

Locations
Country Name City State
Israel Hillel Yaffe Medical Center Hadera

Sponsors (2)
Lead Sponsor Collaborator
Hillel Yaffe Medical Center Technion, Israel Institute of Technology

Country where clinical trial is conducted

Israel, 

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