The HIV Testing Trends and Outcomes at a Johannesburg Trauma ICU Unit

Outcome, Fatal Clinical Trial

Official title:

The HIV Testing Trends and Outcomes at a Johannesburg Trauma ICU Unit

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05484947
• Other study ID #: Witwatersrand
• Status: Completed
• Start date: January 1, 2017
• Est. completion date: August 18, 2021

Study information

• Verified date: July 2022
• Source: University of Witwatersrand, South Africa
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

A retrospective observational study on the HIV testing trend and outcomes in a trauma population admitted to a critical care unit for care.

Description:

Trauma ICU admission of 18 years and older were enrolled in the study. The HIV status was further divided into HIV-positive, HIV-negative, and HIV-unknown subgroups. The gender, ages, mechanism of injury, injuries sustained, ISS, physiological data, septic-related complications, and in-hospital mortality were noted and further analyzed.

Descriptive statistics were utilised using STATA version 15, and a p-value of <0.05 was considered statistically significant.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 868
• Est. completion date: August 18, 2021
• Est. primary completion date: December 31, 2018
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria: Trauma patients admitted to a Trauma ICU at CMJAH -

Exclusion Criteria: Those under the age of 18 or with incomplete data

-

Related Conditions & MeSH terms

• Outcome, Fatal

Intervention

Diagnostic Test:
• Elisa HIV testing
HIV testing on a voluntary basis

Locations

Country	Name	City	State
South Africa	Charlotte Maxeke Johanneburg Academic Hospital	Johannesburg	Gauteng

Sponsors (1)

Lead Sponsor	Collaborator
University of Witwatersrand, South Africa

Country where clinical trial is conducted

South Africa, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The HIV testing trends	Number tested for HIV in the study group	study period over two years (from 01 January 2017 till 31 December 2018)
Primary	Outcomes	Septic related complications (wound infections, chest sepsis, septicaemia and sepsis related organ failure incidents	study period over two years (from 01 January 2017 till 31 December 2018)
Secondary	Mortality	In-hospital mortality in the cohort	study period over two years (from 01 January 2017 till 31 December 2018)