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Outcome, Fatal clinical trials

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NCT ID: NCT06233357 Completed - COVID-19 Clinical Trials

Critically Ill ICU Patients Under Casirivimab- and/or Tocilizumab Application

CasiTocCOVID
Start date: August 1, 2021
Phase:
Study type: Observational

In a retrospective observational study, critically ill COVID-19 patients admitted to the ICU with the CoV-2 delta-variant between august 2021 and february 2022 were evaluated (ethics application nr. 129/22 of the ethics commssion of the university Ulm.

NCT ID: NCT06146270 Not yet recruiting - Surgery Clinical Trials

Russian Registry of Surgical OutcomeS

RuSOS
Start date: March 1, 2024
Phase:
Study type: Observational

Identification of risk factors that cause a high probability of an unfavorable outcome in the postoperative period is an urgent problem. The creation of national databases (registries) makes it possible to maximally cover a certain patient population by identifying its characteristic risk predictors. As literature data show, existing registries differ in the criteria for inclusion in the study, in the characteristics of the populations studied, and there is often no common view on the classification of postoperative outcomes. Goal of a study is a creation of a Russian national calculator for the risk of postoperative complications and mortality. Two-level observational retrospective-prospective study was planned. Setting: National multicenter study of surgical inpatients. Patients: Adult patients undergoing elective and emergency surgery. Types of interventions: in obstetrics, in gynecology, on the breast, in urology and kidneys, in endocrine surgery, in maxillofacial surgery, in orthopedics and traumatology, on the lower floor of the abdominal cavity, on the liver and biliary tract, on the upper floor of the abdominal cavity cavities, in thoracic surgery, in vascular surgery, in neurosurgery, in cardiac surgery, in other areas (with mandatory specification). The study was organized by the Federation of Anesthesiologists and Reanimatologists of Russia. Primary (30-day mortality, 30-day complications) and secondary (hospital mortality, hospital complications, length of stay in anesthesiology, resuscitation and intensive care departments, length of hospital stay, multiple organ failure (2 or more points on the SOFA scale (Sequential)) Organ Failure Assessment), 90-day mortality, 90-day complications, intensive care after-effects syndrome, readmission, 1-year mortality) outcomes were determined. The required sample size and statistical analysis methods are described. The planned duration of the study is 2024-2028.

NCT ID: NCT06036628 Recruiting - Intensive Care Unit Clinical Trials

Resistant Bacteria in Children in France

BREF
Start date: April 1, 2023
Phase:
Study type: Observational

This study is observational, multicenter and prospective study for surveillance of the use of new antibiotics in pediatrics for treated pediatrics infections due to multi-resistant bacteria

NCT ID: NCT06006975 Recruiting - Ischemia Clinical Trials

Early Warning of Delayed Cerebral Ischemia

EWoDCI
Start date: September 21, 2021
Phase:
Study type: Observational

The goal of this observational study is to learn about the possibility to predict clinical course of subarachnoid hemorrhage (SAH) patients by performing the retrospective analysis of clinical data available in early pre-vasospasm phase. The main questions it aims to answer are: - What biomarkers retrieved from Computed Tomography (CT) and Computed Tomography Angiography (SAH location, leaked blood volume, cerebrospinal fluid volume, etc.) can be used to predict development of cerebral vasospasms, delayed cerebral ischemia and patients' outcome. - What biomarkers retrieved from transcranial Doppler examinations in early pre vasospasm can be used to predict development of cerebral vasospasms, delayed cerebral ischemia and patients' outcome. - What biomarkers retrieved from multimodal physiological monitoring in early pre vasospasm can be used to predict development of cerebral vasospasms, delayed cerebral ischemia and patients' outcome. - What is impact of other clinical data (blood test results, age, gender, etc.) on development of cerebral vasospasms and delayed cerebral ischemia.

NCT ID: NCT05983549 Not yet recruiting - Clinical trials for Traumatic Brain Injury

Neutral Versus Liberal fLuId In Traumatic Brain Injury: a Randomised Controlled Trial

LIMIT
Start date: September 1, 2023
Phase: N/A
Study type: Interventional

Feasibility and safety of targeting neutral vs liberal fluid balance in traumatic brain injured patients: a phase II randomized controlled trial

NCT ID: NCT05788861 Recruiting - Risk Factors Clinical Trials

Invasive Group A Streptococcal Infection

ISAI
Start date: September 1, 2022
Phase:
Study type: Observational

This study is observational, retrospective and prospective study in pediatric patients hospitalized with invasive streptococcal A infection

NCT ID: NCT05486494 Completed - Outcome, Fatal Clinical Trials

Spine Registry University Hospital of Cologne- Department of Orthopedics

Start date: January 1, 2008
Phase:
Study type: Observational [Patient Registry]

Between January 2008 and December 2020 all patients with spine diseases were registered prospectively in the former European Spine Tango registry and later german DWG registry at the department of orthopedics and trauma at the university of cologne.

NCT ID: NCT05484947 Completed - Outcome, Fatal Clinical Trials

The HIV Testing Trends and Outcomes at a Johannesburg Trauma ICU Unit

Start date: January 1, 2017
Phase:
Study type: Observational

A retrospective observational study on the HIV testing trend and outcomes in a trauma population admitted to a critical care unit for care.

NCT ID: NCT05338593 Completed - Clinical trials for Extracorporeal Membrane Oxygenation Complication

Therapy and Outcome of Prolonged Veno-venous ECMO Therapy of Critically Ill ARDS Patients.

Start date: May 1, 2022
Phase:
Study type: Observational

In the context of the coronavirus (COVID-19) pandemic, healthcare systems worldwide faced an unprecedented shortage of severe ARDS. Critically affected patients were treated with veno-venous extracorporeal membrane oxygenation (VV-ECMO) for complete respiratory failure early in the pandemic. Due to a shortage of resources in the sense of terminal equipment and adequately trained personnel with appropriate expertise in many countries and regions, a strict selection of suitable patients was made. Repeatedly, it was observed that patients under VV-ECMO also needed several weeks to recover sufficiently to generate device sufficient gas exchange. Due to the scarcity of VV-ECMO resources outside of the pandemic, the question arose whether a prolonged therapy still holds a sufficient prospect of success and what the course of treatment of such patients would be like.

NCT ID: NCT05230719 Recruiting - Clinical trials for Acute Coronary Syndrome

Decrease Artery Occlusion by Distal Radial Arterial Cannulation, Observational Study

DONATION-OB
Start date: January 1, 2019
Phase:
Study type: Observational

The site of arterial access for coronary angiography and intervention has been the focus of research for decades as it is the source of major complications. Transradial access (TRA) reduces complications among patients undergoing percutaneous coronary procedures but is reported with the complication of radial artery occlusion (RAO) that limits the radial artery for future needs. Distal radial access (dTRA) has recently gained global popularity as an alternative access route for vascular procedures. Among the benefits of dTRA are the low risk of entry site bleeding complications, the low rate of radial artery occlusion, and improved patient and operator comfort. This study aims to reveal the feasibility and safety of dTRA and routine TRA procedures in acute coronary syndrome patients. The primary endpoints are forearm radical occlusion rate and major adverse cardiovascular events (MACEs) in the two groups. Investigators conduct this retrospected analysis to demonstrate the difference of the two procedure of Cannulation.