Perioperative Database of Chinese Elderly Patients for Postoperative Acute Kidney Injury

Postoperative Acute Kidney Injury Clinical Trial

Official title:

Perioperative Database of Chinese Elderly Patients for Postoperative Acute Kidney Injury

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06462755
• Other study ID #: PLAGH-AOC-R01
• Status: Completed
• Start date: January 1, 2009
• Est. completion date: December 31, 2018

Study information

• Verified date: June 2024
• Source: Chinese PLA General Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

To develop and externally validate a risk prediction model for postoperative acute kidney injury (PO-AKI) in elderly patients undergoing major noncardiac surgery, addressing the current gap in predictive tools for this vulnerable population. The endpoint was the occurrence of PO-AKI within seven days following surgery. Diagnoses were based on the Kidney Disease: Improving Global Outcomes (KDIGO) criterion. Potential PO-AKI-related perioperative data were retrieved and extracted from electronic medical record for model derivation and validation. Clinicians may consider implementing this externally validated risk prediction model to stratify elderly patients' PO-AKI risks in the early postoperative phases of noncardiac surgery in elderly patients.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 57089
• Est. completion date: December 31, 2018
• Est. primary completion date: December 31, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 65 Years to 120 Years

Eligibility

Inclusion Criteria:

• elderly patients (aged = 65 years) undergoing non-cardiac surgeries

Exclusion Criteria:

• (1) Patients who underwent endoscopic or transplant procedures;
• (2) Patients who underwent surgeries lasting longer than 10 hours;
• (3) Patients who had severe preoperative kidney dysfunction, defined as preoperative sCr levels = 353.6 µmol/L, or a baseline estimated Glomerular Filtration Rate (eGFR) < 15 ml/min per 1.73 m2;
• (4) Patients without sCr values at baseline or during follow-up to detect PO-AKI occurrences.

Related Conditions & MeSH terms

• Acute Kidney Injury
• Postoperative Acute Kidney Injury
• Wounds and Injuries

Intervention

Other:
• No intervention
no intervention

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Chinese PLA General Hospital

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Postoperative acute kidney injury	Postoperative acute kidney injury	within seven days following surgery